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Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization.
Strauss A, Gonzalez-Hernandez AJ, Lee J, Abreu N, Selvakumar P, Salas-Estrada L, Kristt M, Marx DC, Gilliland K, Melancon BJ, Filizola M, Meyerson J, Levitz J. Strauss A, et al. Among authors: levitz j. bioRxiv [Preprint]. 2023 Aug 14:2023.08.13.552748. doi: 10.1101/2023.08.13.552748. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 1;15(1):6498. doi: 10.1038/s41467-024-50548-x PMID: 37645747 Free PMC article. Updated. Preprint.
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains.
Mancinelli C, Marx DC, Gonzalez-Hernandez AJ, Huynh K, Mancinelli L, Arefin A, Khelashvilli G, Levitz J, Eliezer D. Mancinelli C, et al. Among authors: levitz j. bioRxiv [Preprint]. 2024 May 2:2023.08.16.553551. doi: 10.1101/2023.08.16.553551. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2407744121. doi: 10.1073/pnas.2407744121 PMID: 37645938 Free PMC article. Updated. Preprint.
Projection-Targeted Photopharmacology Reveals Distinct Anxiolytic Roles for Presynaptic mGluR2 in Prefrontal- and Insula-Amygdala Synapses.
Munguba H, Gutzeit VA, Srivastava I, Kristt M, Singh A, Vijay A, Arefin A, Thukral S, Broichhagen J, Stujenske JM, Liston C, Levitz J. Munguba H, et al. Among authors: levitz j. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575699. doi: 10.1101/2024.01.15.575699. bioRxiv. 2024. PMID: 38293136 Free PMC article. Preprint.
Deuteration as a General Strategy to Enhance Azobenzene-Based Photopharmacology.
Roßmann K, Gonzalez-Hernandez AJ, Bhuyan R, Schattenberg C, Sun H, Börjesson K, Levitz J, Broichhagen J. Roßmann K, et al. Among authors: levitz j. Angew Chem Int Ed Engl. 2024 Sep 23;63(39):e202408300. doi: 10.1002/anie.202408300. Epub 2024 Aug 19. Angew Chem Int Ed Engl. 2024. PMID: 38897926
An epigenetic barrier sets the timing of human neuronal maturation.
Ciceri G, Baggiolini A, Cho HS, Kshirsagar M, Benito-Kwiecinski S, Walsh RM, Aromolaran KA, Gonzalez-Hernandez AJ, Munguba H, Koo SY, Xu N, Sevilla KJ, Goldstein PA, Levitz J, Leslie CS, Koche RP, Studer L. Ciceri G, et al. Among authors: levitz j. Nature. 2024 Feb;626(8000):881-890. doi: 10.1038/s41586-023-06984-8. Epub 2024 Jan 31. Nature. 2024. PMID: 38297124 Free PMC article.
Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia.
Martínez-Rivera A, Fetcho RN, Birmingham L, Jiu JX, Yang R, Foord C, Scala-Chávez D, Mekawy N, Pleil K, Pickel VM, Liston C, Castorena CM, Levitz J, Pan YX, Briand LA, Rajadhyaksha AM, Lee FS. Martínez-Rivera A, et al. Among authors: levitz j. bioRxiv [Preprint]. 2024 Apr 2:2024.04.02.585967. doi: 10.1101/2024.04.02.585967. bioRxiv. 2024. Update in: Sci Adv. 2024 Nov 29;10(48):eadq4779. doi: 10.1126/sciadv.adq4779 PMID: 38766079 Free PMC article. Updated. Preprint.
Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia.
Martínez-Rivera A, Fetcho RN, Birmingham L, Xu J, Yang R, Foord C, Scala-Chávez D, Mekawy N, Pleil K, Pickel VM, Liston C, Castorena CM, Levitz J, Pan YX, Briand LA, Rajadhyaksha AM, Lee FS. Martínez-Rivera A, et al. Among authors: levitz j. Sci Adv. 2024 Nov 29;10(48):eadq4779. doi: 10.1126/sciadv.adq4779. Epub 2024 Nov 29. Sci Adv. 2024. PMID: 39612328 Free PMC article.
71 results