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iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
Glia. 2024 Feb;72(2):452-469. doi: 10.1002/glia.24485. Epub 2023 Nov 15.
Glia. 2024.
PMID: 37969043
Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model.
Stanton AE, Bubnys A, Agbas E, James B, Park DS, Jiang A, Pinals RL, Liu L, Truong N, Loon A, Staab C, Cerit O, Wen HL, Kellis M, Blanchard JW, Langer R, Tsai LH.
Stanton AE, et al. Among authors: cerit o.
bioRxiv [Preprint]. 2024 Jun 11:2023.08.15.553453. doi: 10.1101/2023.08.15.553453.
bioRxiv. 2024.
PMID: 37645757
Free PMC article.
Preprint.
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Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity.
Victor MB, Leary N, Luna X, Meharena HS, Scannail AN, Bozzelli PL, Samaan G, Murdock MH, von Maydell D, Effenberger AH, Cerit O, Wen HL, Liu L, Welch G, Bonner M, Tsai LH.
Victor MB, et al. Among authors: cerit o.
Cell Stem Cell. 2022 Aug 4;29(8):1197-1212.e8. doi: 10.1016/j.stem.2022.07.005.
Cell Stem Cell. 2022.
PMID: 35931030
Free PMC article.
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