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Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies.
Ang Z, Paruzzo L, Hayer KE, Schmidt C, Torres Diz M, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, King Sainos P, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Lieberman PM, Ruella M, Schuster SJ, Thomas-Tikhonenko A. Ang Z, et al. bioRxiv [Preprint]. 2023 Aug 16:2023.02.19.529123. doi: 10.1101/2023.02.19.529123. bioRxiv. 2023. Update in: Blood. 2023 Nov 16;142(20):1724-1739. doi: 10.1182/blood.2023020400 PMID: 37645778 Free PMC article. Updated. Preprint.
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C. Hart LS, et al. J Clin Invest. 2012 Dec;122(12):4621-34. doi: 10.1172/JCI62973. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143306 Free PMC article.
MYC and the art of microRNA maintenance.
Psathas JN, Thomas-Tikhonenko A. Psathas JN, et al. Cold Spring Harb Perspect Med. 2014 Apr 15;4(8):a014175. doi: 10.1101/cshperspect.a014175. Cold Spring Harb Perspect Med. 2014. PMID: 24737842 Free PMC article. Review.
Infection and cancer: the common vein.
Thomas-Tikhonenko A, Hunter CA. Thomas-Tikhonenko A, et al. Cytokine Growth Factor Rev. 2003 Feb;14(1):67-77. doi: 10.1016/s1359-6101(02)00071-0. Cytokine Growth Factor Rev. 2003. PMID: 12485620 Review.
91 results