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210 results

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Page 1
Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
Nagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL. Nagy N, et al. Among authors: knowles jw. Cells. 2024 Oct 18;13(20):1727. doi: 10.3390/cells13201727. Cells. 2024. PMID: 39451245 Free PMC article.
One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.
Kim DS, Chu EL, Keamy-Minor EE, Paranjpe ID, Tang WL, O'Sullivan JW, Desai YB, Liu MB, Munsey E, Hecker K, Cuenco I, Kao B, Bacolor E, Bonnett C, Linder A, Lacar K, Robles N, Lamendola C, Smith A, Knowles JW, Perez MV, Kawana M, Sallam KI, Weldy CS, Wheeler MT, Parikh VN, Salisbury H, Ashley EA; Stanford Center for Inherited Cardiovascular Disease. Kim DS, et al. Among authors: knowles jw. Front Cardiovasc Med. 2024 Aug 30;11:1429230. doi: 10.3389/fcvm.2024.1429230. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 39314763 Free PMC article.
A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes.
Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Björck HM, Eriksson P, Schurr TM, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW. Saliba-Gustafsson P, et al. Among authors: knowles jw. Hepatology. 2024 Aug 27. doi: 10.1097/HEP.0000000000001066. Online ahead of print. Hepatology. 2024. PMID: 39190705
Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes.
Yu GZ, Krentz NAJ, Bentley L, Zhao M, Paphiti K, Sun H, Honecker J, Nygård M, Dashti H, Bai Y, Reid M, Thaman S, Wabitsch M, Rajesh V, Yang J, Mattis KK, Abaitua F, Casero R, Hauner H, Knowles JW, Wu JY, Mandrup S, Claussnitzer M, Svensson KJ, Cox RD, Gloyn AL. Yu GZ, et al. Among authors: knowles jw. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605923. doi: 10.1101/2024.07.30.605923. bioRxiv. 2024. PMID: 39131393 Free PMC article. Preprint.
X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction.
Zhang P, Munier JJ, Wiese CB, Vergnes L, Link JC, Abbasi F, Ronquillo E, Scheker K, Muñoz A, Kuang YL, Theusch E, Lu M, Sanchez G, Oni-Orisan A, Iribarren C, McPhaul MJ, Nomura DK, Knowles JW, Krauss RM, Medina MW, Reue K. Zhang P, et al. Among authors: knowles jw. Nat Commun. 2024 Jul 2;15(1):5571. doi: 10.1038/s41467-024-49764-2. Nat Commun. 2024. PMID: 38956041 Free PMC article.
Design and pilot results from the Million Veteran Program Return Of Actionable Results (MVP-ROAR) Study.
Vassy JL, Brunette CA, Yi T, Harrison A, Cardellino MP, Assimes TL, Christensen KD, Devineni P, Gaziano JM, Gong X, Hui Q, Knowles JW, Muralidhar S, Natarajan P, Pyarajan S, Sears MG, Shi Y, Sturm AC, Whitbourne SB, Sun YV, Danowski ME; Million Veteran Program. Vassy JL, et al. Among authors: knowles jw. Am Heart J. 2024 Oct;276:99-109. doi: 10.1016/j.ahj.2024.04.021. Epub 2024 May 17. Am Heart J. 2024. PMID: 38762090 Clinical Trial.
210 results