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CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease.
Sharma A, Boelens JJ, Cancio M, Hankins JS, Bhad P, Azizy M, Lewandowski A, Zhao X, Chitnis S, Peddinti R, Zheng Y, Kapoor N, Ciceri F, Maclachlan T, Yang Y, Liu Y, Yuan J, Naumann U, Yu VWC, Stevenson SC, De Vita S, LaBelle JL. Sharma A, et al. Among authors: yu vwc. N Engl J Med. 2023 Aug 31;389(9):820-832. doi: 10.1056/NEJMoa2215643. N Engl J Med. 2023. PMID: 37646679 Free PMC article. Clinical Trial.
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf RZ, Saez B, Sharda A, van Gastel N, Yu VWC, Baryawno N, Scadden EW, Acharya S, Chattophadhyay S, Huang C, Viswanathan V, S'aulis D, Cobert J, Sykes DB, Keibler MA, Das S, Hutchinson JN, Churchill M, Mukherjee S, Lee D, Mercier F, Doench J, Bullinger L, Logan DJ, Schreiber S, Stephanopoulos G, Rizzo WB, Scadden DT. Yusuf RZ, et al. Among authors: yu vwc. Blood. 2020 Sep 10;136(11):1303-1316. doi: 10.1182/blood.2019001808. Blood. 2020. PMID: 32458004 Free PMC article.
Heterogeneity of the bone marrow niche.
Yu VW, Scadden DT. Yu VW, et al. Curr Opin Hematol. 2016 Jul;23(4):331-8. doi: 10.1097/MOH.0000000000000265. Curr Opin Hematol. 2016. PMID: 27177311 Free PMC article. Review.
Hematopoietic Stem Cell and Its Bone Marrow Niche.
Yu VW, Scadden DT. Yu VW, et al. Curr Top Dev Biol. 2016;118:21-44. doi: 10.1016/bs.ctdb.2016.01.009. Epub 2016 Mar 21. Curr Top Dev Biol. 2016. PMID: 27137653 Free PMC article. Review.
25 results