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Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators.
Sun JY, Kumata K, Chen Z, Zhang YD, Chen JH, Hatori A, Fu HL, Rong J, Deng XY, Yamasaki T, Xie L, Hu K, Fujinaga M, Yu QZ, Shao T, Collier TL, Josephson L, Shao YH, Du YF, Wang L, Xu H, Zhang MR, Liang SH. Sun JY, et al. Among authors: chen z, chen jh. Acta Pharmacol Sin. 2021 Mar;42(3):491-498. doi: 10.1038/s41401-020-0456-9. Epub 2020 Jul 13. Acta Pharmacol Sin. 2021. PMID: 32661351 Free PMC article.
Assessment of cholesterol homeostasis in the living human brain.
Haider A, Zhao C, Wang L, Xiao Z, Rong J, Xia X, Chen Z, Pfister SK, Mast N, Yutuc E, Chen J, Li Y, Shao T, Warnock GI, Dawoud A, Connors TR, Oakley DH, Wei H, Wang J, Zheng Z, Xu H, Davenport AT, Daunais JB, Van RS, Shao Y, Wang Y, Zhang MR, Gebhard C, Pikuleva I, Levey AI, Griffiths WJ, Liang SH. Haider A, et al. Among authors: chen z, chen j. Sci Transl Med. 2022 Oct 5;14(665):eadc9967. doi: 10.1126/scitranslmed.adc9967. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197966 Free PMC article.
Small-animal PET study for noninvasive quantification of transmembrane AMPA receptor regulatory protein γ-8 (TARP γ-8) in the brain.
Yamasaki T, Ishii H, Hiraishi A, Kumata K, Wakizaka H, Zhang Y, Kurihara Y, Ogawa M, Nengaki N, Chen J, Li Y, Liang S, Zhang MR. Yamasaki T, et al. Among authors: chen j. J Cereb Blood Flow Metab. 2023 Jun;43(6):893-904. doi: 10.1177/0271678X231152025. Epub 2023 Jan 18. J Cereb Blood Flow Metab. 2023. PMID: 36655318 Free PMC article.
Quantitative assessment of translocator protein (TSPO) in the non-human primate brain and clinical translation of [18F]LW223 as a TSPO-targeted PET radioligand.
Tan Z, Haider A, Zhang S, Chen J, Wei J, Liao K, Li G, Wei H, Dong C, Ran W, Li Y, Li Y, Rong J, Li Y, Liang SH, Xu H, Wang L. Tan Z, et al. Among authors: chen j. Pharmacol Res. 2023 Mar;189:106681. doi: 10.1016/j.phrs.2023.106681. Epub 2023 Feb 4. Pharmacol Res. 2023. PMID: 36746361 Free article.
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors.
Korff M, Chaudhary A, Li Y, Zhou X, Zhao C, Rong J, Chen J, Xiao Z, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Wang L, Abate C, Ahmed H, Crowe R, Liang SH, Ametamey SM, Wünsch B, Haider A. Korff M, et al. Among authors: chen j. Res Sq [Preprint]. 2023 Jan 27:rs.3.rs-2516002. doi: 10.21203/rs.3.rs-2516002/v1. Res Sq. 2023. Update in: J Med Chem. 2023 Dec 14;66(23):16018-16031. doi: 10.1021/acs.jmedchem.3c01441 PMID: 36747738 Free PMC article. Updated. Preprint.
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