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Page 1
Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity.
Syed A, Filandr F, Patterson-Fortin J, Bacolla A, Ravindranathan R, Zhou J, McDonald DT, Albuhluli ME, Verway-Cohen A, Newman JA, Tsai MS, Jones DE, Schriemer DC, D'Andrea AD, Tainer JA. Syed A, et al. Among authors: bacolla a. Nucleic Acids Res. 2023 Oct 13;51(18):9920-9937. doi: 10.1093/nar/gkad727. Nucleic Acids Res. 2023. PMID: 37665033 Free PMC article.
GRB2 enforces homology-directed repair initiation by MRE11.
Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, Tsai CL, Shen Q, Peng G, Leonard PG, Jones DE, Wang B, Tainer JA, Ahmed Z. Ye Z, et al. Among authors: bacolla a. Sci Adv. 2021 Aug 4;7(32):eabe9254. doi: 10.1126/sciadv.abe9254. Print 2021 Aug. Sci Adv. 2021. PMID: 34348893 Free PMC article.
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.
Tsutakawa SE, Sarker AH, Ng C, Arvai AS, Shin DS, Shih B, Jiang S, Thwin AC, Tsai MS, Willcox A, Her MZ, Trego KS, Raetz AG, Rosenberg D, Bacolla A, Hammel M, Griffith JD, Cooper PK, Tainer JA. Tsutakawa SE, et al. Among authors: bacolla a. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14127-14138. doi: 10.1073/pnas.1921311117. Epub 2020 Jun 10. Proc Natl Acad Sci U S A. 2020. PMID: 32522879 Free PMC article.
86 results