Kok CY - Search Results

1

Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes.

Kok CY, Tsurusaki S, Cabanes-Creus M, Igoor S, Rao R, Skelton R, Liao SHY, Ginn SL, Knight M, Scott S, Mietzsch M, Fitzsimmons R, Miller J, Mohamed TMA, McKenna R, Chong JJH, Hill AP, Hudson JE, Alexander IE, Lisowski L, Kizana E. Kok CY, et al. Mol Ther Methods Clin Dev. 2023 Aug 18;30:459-473. doi: 10.1016/j.omtm.2023.08.010. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37674904 Free PMC article.

2

Induction and prevention of severe hyperammonemia in the spfash mouse model of ornithine transcarbamylase deficiency using shRNA and rAAV-mediated gene delivery.

Cunningham SC, Kok CY, Dane AP, Carpenter K, Kizana E, Kuchel PW, Alexander IE. Cunningham SC, et al. Among authors: kok cy. Mol Ther. 2011 May;19(5):854-9. doi: 10.1038/mt.2011.32. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386824 Free PMC article.

3

Gene therapy for metabolic disorders: an overview with a focus on urea cycle disorders.

Alexander IE, Kok C, Dane AP, Cunningham SC. Alexander IE, et al. J Inherit Metab Dis. 2012 Jul;35(4):641-5. doi: 10.1007/s10545-012-9467-0. Epub 2012 Mar 9. J Inherit Metab Dis. 2012. PMID: 22403018

4

Adeno-associated virus-mediated rescue of neonatal lethality in argininosuccinate synthetase-deficient mice.

Kok CY, Cunningham SC, Carpenter KH, Dane AP, Siew SM, Logan GJ, Kuchel PW, Alexander IE. Kok CY, et al. Mol Ther. 2013 Oct;21(10):1823-31. doi: 10.1038/mt.2013.139. Epub 2013 Jul 2. Mol Ther. 2013. PMID: 23817206 Free PMC article.

5

AAV-encoded OTC activity persisting to adulthood following delivery to newborn spf(ash) mice is insufficient to prevent shRNA-induced hyperammonaemia.

Cunningham SC, Kok CY, Spinoulas A, Carpenter KH, Alexander IE. Cunningham SC, et al. Among authors: kok cy. Gene Ther. 2013 Dec;20(12):1184-7. doi: 10.1038/gt.2013.51. Epub 2013 Oct 10. Gene Ther. 2013. PMID: 24108150

6

Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus.

Dane AP, Cunningham SC, Kok CY, Logan GJ, Alexander IE. Dane AP, et al. Among authors: kok cy. Gene Ther. 2015 Nov;22(11):917-22. doi: 10.1038/gt.2015.66. Epub 2015 Jul 30. Gene Ther. 2015. PMID: 26224361

7

Directed Evolution of Adeno-Associated Virus Vectors in Human Cardiomyocytes for Cardiac Gene Therapy.

Kok CY, Alexander I, Lisowski L, Kizana E. Kok CY, et al. Heart Lung Circ. 2018 Nov;27(11):1270-1273. doi: 10.1016/j.hlc.2018.08.014. Heart Lung Circ. 2018. PMID: 30274736 No abstract available.

8

Insights into Gene Therapy for Urea Cycle Defects by Mathematical Modeling.

Kok CY, Cunningham SC, Kuchel PW, Alexander IE. Kok CY, et al. Hum Gene Ther. 2019 Nov;30(11):1385-1394. doi: 10.1089/hum.2019.053. Epub 2019 Jul 17. Hum Gene Ther. 2019. PMID: 31215258

9

Analysis of recombinant adeno-associated viral vector shedding in sheep following intracoronary delivery.

Farraha M, Barry MA, Lu J, Pouliopoulos J, Le TYL, Igoor S, Rao R, Kok C, Chong J, Kizana E. Farraha M, et al. Gene Ther. 2019 Sep;26(9):399-406. doi: 10.1038/s41434-019-0097-0. Epub 2019 Aug 29. Gene Ther. 2019. PMID: 31467408

10

Gene and Cell Therapy for Cardiac Arrhythmias.

Ravindran D, Kok C, Farraha M, Selvakumar D, Clayton ZE, Kumar S, Chong J, Kizana E. Ravindran D, et al. Clin Ther. 2020 Oct;42(10):1911-1922. doi: 10.1016/j.clinthera.2020.09.001. Epub 2020 Sep 26. Clin Ther. 2020. PMID: 32988632 Review.

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