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Page 1
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.
Vagnozzi RJ, Gatto GJ Jr, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T. Vagnozzi RJ, et al. Sci Transl Med. 2013 Oct 16;5(207):207ra141. doi: 10.1126/scitranslmed.3006479. Sci Transl Med. 2013. PMID: 24132636 Free PMC article.
GSK-3α is a central regulator of age-related pathologies in mice.
Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y, Ma XL, Woodgett J, Vagnozzi RJ, Lal H, Force T. Zhou J, et al. Among authors: vagnozzi rj. J Clin Invest. 2013 Apr;123(4):1821-32. doi: 10.1172/JCI64398. Epub 2013 Mar 15. J Clin Invest. 2013. PMID: 23549082 Free PMC article.
c-kit+ cells minimally contribute cardiomyocytes to the heart.
van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC, Middleton RC, Marbán E, Molkentin JD. van Berlo JH, et al. Among authors: vagnozzi rj. Nature. 2014 May 15;509(7500):337-41. doi: 10.1038/nature13309. Epub 2014 May 7. Nature. 2014. PMID: 24805242 Free PMC article.
Author Correction: Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, Mass E, Ishikawa-Ankerhold HC, Margraf A, Hutter S, Vagnozzi R, Klapproth S, Frampton J, Yona S, Scheiermann C, Molkentin JD, Jeschke U, Moser M, Sperandio M, Massberg S, Geissmann F, Schulz C. Stremmel C, et al. Nat Commun. 2018 Sep 7;9(1):3699. doi: 10.1038/s41467-018-06065-9. Nat Commun. 2018. PMID: 30194428 Free PMC article.
An acute immune response underlies the benefit of cardiac stem cell therapy.
Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen AKZ, Schwanekamp JA, York AJ, Huang V, Nahrendorf M, Sadayappan S, Molkentin JD. Vagnozzi RJ, et al. Nature. 2020 Jan;577(7790):405-409. doi: 10.1038/s41586-019-1802-2. Epub 2019 Nov 27. Nature. 2020. PMID: 31775156 Free PMC article.
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation.
Weinberger T, Esfandyari D, Messerer D, Percin G, Schleifer C, Thaler R, Liu L, Stremmel C, Schneider V, Vagnozzi RJ, Schwanenkamp J, Fischer M, Busch K, Klapproth K, Ishikawa-Ankerhold H, Klösges L, Titova A, Molkentin JD, Kobayashi Y, Engelhardt S, Massberg S, Waskow C, Perdiguero EG, Schulz C. Weinberger T, et al. Among authors: vagnozzi rj. Nat Commun. 2020 Sep 11;11(1):4549. doi: 10.1038/s41467-020-18287-x. Nat Commun. 2020. PMID: 32917889 Free PMC article.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Among authors: vagnozzi rj. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
53 results