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324 results

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Page 1
Substrate binding and inhibition of the anion exchanger 1 transporter.
Capper MJ, Yang S, Stone AC, Vatansever S, Zilberg G, Mathiharan YK, Habib R, Hutchinson K, Zhao Y, Schlessinger A, Mezei M, Osman R, Zhang B, Wacker D. Capper MJ, et al. Among authors: hutchinson k. Nat Struct Mol Biol. 2023 Oct;30(10):1495-1504. doi: 10.1038/s41594-023-01085-6. Epub 2023 Sep 7. Nat Struct Mol Biol. 2023. PMID: 37679563 Free PMC article.
An ID2-dependent mechanism for VHL inactivation in cancer.
Lee SB, Frattini V, Bansal M, Castano AM, Sherman D, Hutchinson K, Bruce JN, Califano A, Liu G, Cardozo T, Iavarone A, Lasorella A. Lee SB, et al. Among authors: hutchinson k. Nature. 2016 Jan 14;529(7585):172-7. doi: 10.1038/nature16475. Epub 2016 Jan 6. Nature. 2016. PMID: 26735018 Free PMC article.
Inavolisib-Based Therapy in PIK3CA-Mutated Advanced Breast Cancer.
Turner NC, Im SA, Saura C, Juric D, Loibl S, Kalinsky K, Schmid P, Loi S, Sunpaweravong P, Musolino A, Li H, Zhang Q, Nowecki Z, Leung R, Thanopoulou E, Shankar N, Lei G, Stout TJ, Hutchinson KE, Schutzman JL, Song C, Jhaveri KL. Turner NC, et al. Among authors: hutchinson ke. N Engl J Med. 2024 Oct 31;391(17):1584-1596. doi: 10.1056/NEJMoa2404625. N Engl J Med. 2024. PMID: 39476340 Clinical Trial.
Conditional Knockout of Striatal Gnal Produces Dystonia-like Motor Phenotypes.
Chambers NE, Hall D, Barsoum S, Miller E, Curry T, Kaplan M, Garan S, Gallardo I, Staab R, Nabert D, Hutchinson K, Millett M, Moehle MS. Chambers NE, et al. Among authors: hutchinson k. bioRxiv [Preprint]. 2024 Aug 28:2024.08.26.609754. doi: 10.1101/2024.08.26.609754. bioRxiv. 2024. PMID: 39253490 Free PMC article. Preprint.
Phase I/Ib Trial of Inavolisib Plus Palbociclib and Endocrine Therapy for PIK3CA-Mutated, Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced or Metastatic Breast Cancer.
Jhaveri KL, Accordino MK, Bedard PL, Cervantes A, Gambardella V, Hamilton E, Italiano A, Kalinsky K, Krop IE, Oliveira M, Schmid P, Saura C, Turner NC, Varga A, Cheeti S, Hilz S, Hutchinson KE, Jin Y, Royer-Joo S, Peters U, Shankar N, Schutzman JL, Juric D. Jhaveri KL, et al. Among authors: hutchinson ke. J Clin Oncol. 2024 Nov 20;42(33):3947-3956. doi: 10.1200/JCO.24.00110. Epub 2024 Sep 5. J Clin Oncol. 2024. PMID: 39236276 Free PMC article. Clinical Trial.
324 results