Frazer IH - Search Results

1

Deep spatial-omics analysis of Head & Neck carcinomas provides alternative therapeutic targets and rationale for treatment failure.

Causer A, Tan X, Lu X, Moseley P, Teoh SM, Molotkov N, McGrath M, Kim T, Simpson PT, Perry C, Frazer IH, Panizza B, Ladwa R, Nguyen Q, Gonzalez-Cruz JL. Causer A, et al. Among authors: frazer ih. NPJ Precis Oncol. 2023 Sep 13;7(1):89. doi: 10.1038/s41698-023-00444-2. NPJ Precis Oncol. 2023. PMID: 37704757 Free PMC article.

2

Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicity.

Wright QG, Sinha D, Wells JW, Frazer IH, Gonzalez Cruz JL, Leggatt GR. Wright QG, et al. Among authors: frazer ih. J Immunother Cancer. 2024 Jan 31;12(1):e007960. doi: 10.1136/jitc-2023-007960. J Immunother Cancer. 2024. PMID: 38296598 Free PMC article.

3

A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma.

Ladwa R, Chandra J, Woo WP, Finlayson N, Liu H, McGrath M, See A, Hughes BG, Cooper CL, Jackson JE, Dzienis M, Xu Y, Panizza B, Frazer I, Porceddu SV. Ladwa R, et al. Front Oncol. 2024 Jul 5;14:1419258. doi: 10.3389/fonc.2024.1419258. eCollection 2024. Front Oncol. 2024. PMID: 39035738 Free PMC article.

4

HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer.

Mehdi AM, Zhou C, Turrell G, Walpole E, Porceddu S, Frazer IH, Chandra J. Mehdi AM, et al. Among authors: frazer ih. Cancer Gene Ther. 2023 Apr;30(4):629-640. doi: 10.1038/s41417-022-00577-9. Epub 2022 Dec 27. Cancer Gene Ther. 2023. PMID: 36575316 Free PMC article.

5

Targeting Staphylococcus aureus dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?

Bromfield JI, Hugenholtz P, Frazer IH, Khosrotehrani K, Chandra J. Bromfield JI, et al. Among authors: frazer ih. Front Oncol. 2023 Feb 2;13:1091379. doi: 10.3389/fonc.2023.1091379. eCollection 2023. Front Oncol. 2023. PMID: 36816953 Free PMC article.

6

Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts.

Veitch M, Beaumont K, Pouwer R, Chew HY, Frazer IH, Soyer HP, Campbell S, Dymock BW, Harvey A, Cock TA, Wells JW. Veitch M, et al. Among authors: frazer ih. J Immunother Cancer. 2023 Sep;11(9):e006783. doi: 10.1136/jitc-2023-006783. J Immunother Cancer. 2023. PMID: 37678918 Free PMC article.

7

Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene-environment associations.

Muralidharan S, Ali S, Yang L, Badshah J, Zahir SF, Ali RA, Chandra J, Frazer IH, Thomas R, Mehdi AM. Muralidharan S, et al. Among authors: frazer ih. Sci Rep. 2022 Nov 4;12(1):18710. doi: 10.1038/s41598-022-21988-6. Sci Rep. 2022. PMID: 36333579 Free PMC article.

8

STING Nanoagonist Boosts Antitumor Immunity of Therapeutic DNA Vaccines.

Jia W, Chandra J, Teoh SM, Tolley L, Yang H, Tse BWC, Sokolowski KA, Liang X, Crawford DHG, Steel JC, Yu C, Roberts MS, Frazer IH, Chen Y, Wang H, Yu M. Jia W, et al. Among authors: frazer ih. Nano Lett. 2024 Dec 11;24(49):15588-15597. doi: 10.1021/acs.nanolett.4c03846. Epub 2024 Dec 2. Nano Lett. 2024. PMID: 39621441

9

Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen-processing-presentation machinery and poor patient survival.

Dang TVT, Gillinder KR, Nguyen Q, Mulay O, Vo T, Mehdi AM, Zhou C, Brooks AJ, Leggatt GR, Hume DA, Frazer IH, Chandra J. Dang TVT, et al. Among authors: frazer ih. Clin Transl Immunology. 2024 Nov 29;13(12):e70018. doi: 10.1002/cti2.70018. eCollection 2024. Clin Transl Immunology. 2024. PMID: 39619016 Free PMC article.

10

Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs.

Bromfield JI, Zaugg J, Straw RC, Cathie J, Krueger A, Sinha D, Chandra J, Hugenholtz P, Frazer IH. Bromfield JI, et al. Among authors: frazer ih. mSphere. 2024 Apr 23;9(4):e0055523. doi: 10.1128/msphere.00555-23. Epub 2024 Mar 26. mSphere. 2024. PMID: 38530017 Free PMC article.

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