Tower RJ - Search Results

1

Itaconate-producing neutrophils regulate local and systemic inflammation following trauma.

Crossley JL, Ostashevskaya-Gohstand S, Comazzetto S, Hook JS, Guo L, Vishlaghi N, Juan C, Xu L, Horswill AR, Hoxhaj G, Moreland JG, Tower RJ, Levi B. Crossley JL, et al. Among authors: tower rj. JCI Insight. 2023 Oct 23;8(20):e169208. doi: 10.1172/jci.insight.169208. JCI Insight. 2023. PMID: 37707952 Free PMC article.

2

Mapping Somatosensory Afferent Circuitry to Bone Identifies Neurotrophic Signals Required for Fracture Healing.

Xu M, Thottappillil N, Cherief M, Li Z, Zhu M, Xing X, Gomez-Salazar M, Mwirigi JM, Sankaranarayanan I, Tavares-Ferreira D, Zhang C, Wang XW, Archer M, Guan Y, Tower RJ, Cahan P, Price TJ, Clemens TL, James AW. Xu M, et al. Among authors: tower rj. bioRxiv [Preprint]. 2024 Jun 7:2024.06.06.597786. doi: 10.1101/2024.06.06.597786. bioRxiv. 2024. PMID: 38895367 Free PMC article. Preprint.

3

Neutrophil and NETosis Modulation in Traumatic Heterotopic Ossification.

Nunez JH, Juan C, Sun Y, Hong J, Bancroft AC, Hwang C, Medrano JM, Huber AK, Tower RJ, Levi B. Nunez JH, et al. Among authors: tower rj. Ann Surg. 2023 Dec 1;278(6):e1289-e1298. doi: 10.1097/SLA.0000000000005940. Epub 2023 Jun 16. Ann Surg. 2023. PMID: 37325925 Free PMC article.

4

Vegfc-expressing cells form heterotopic bone after musculoskeletal injury.

Vishlaghi N, Guo L, Griswold-Wheeler D, Sun Y, Booker C, Crossley JL, Bancroft AC, Juan C, Korlakunta S, Ramesh S, Pagani CA, Xu L, James AW, Tower RJ, Dellinger M, Levi B. Vishlaghi N, et al. Among authors: tower rj. Cell Rep. 2024 Apr 23;43(4):114049. doi: 10.1016/j.celrep.2024.114049. Epub 2024 Apr 3. Cell Rep. 2024. PMID: 38573853 Free article.

5

Spatial transcriptomics implicates impaired BMP signaling in NF1 fracture pseudarthrosis in murine and patient tissues.

Rios JJ, Juan C, Shelton JM, Paria N, Oxendine I, Wassell M, Kidane YH, Cornelia R, Jeffery EC, Podeszwa DA, Conway SJ, Wise CA, Tower RJ. Rios JJ, et al. Among authors: tower rj. JCI Insight. 2024 Jul 11;9(16):e176802. doi: 10.1172/jci.insight.176802. JCI Insight. 2024. PMID: 38990653 Free PMC article.

6

Nr4a1 enhances Wnt4 transcription to promote mesenchymal stem cell osteogenesis and alleviates inflammation-inhibited bone regeneration.

Gao Y, Zou Y, Sokolowskei D, Xing X, Tower RJ, Lai Z, Shi J, Zhu L, Zheng Q, James AW, Xu J, Zhang Z. Gao Y, et al. Among authors: tower rj. Mol Ther. 2024 May 1;32(5):1479-1496. doi: 10.1016/j.ymthe.2024.02.034. Epub 2024 Mar 1. Mol Ther. 2024. PMID: 38429926

7

The Mohawk homeobox gene represents a marker and osteo-inhibitory factor in calvarial suture osteoprogenitor cells.

Wang Y, Qin Q, Wang Z, Negri S, Sono T, Tower RJ, Li Z, Xing X, Archer M, Thottappillil N, Zhu M, Suarez A, Kim DH, Harvey T, Fan CM, James AW. Wang Y, et al. Among authors: tower rj. Cell Death Dis. 2024 Jun 17;15(6):420. doi: 10.1038/s41419-024-06813-4. Cell Death Dis. 2024. PMID: 38886383 Free PMC article.

8

Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells.

Wang Y, Thottappillil N, Gomez-Salazar M, Tower RJ, Qin Q, Del Rosario Alvia IC, Xu M, Cherief M, Cheng R, Archer M, Arondekar S, Reddy S, Broderick K, Péault B, James AW. Wang Y, et al. Among authors: tower rj. Dev Cell. 2024 Oct 21;59(20):2687-2703.e6. doi: 10.1016/j.devcel.2024.06.015. Epub 2024 Jul 17. Dev Cell. 2024. PMID: 39025061

9

Glutaminolysis provides nucleotides and amino acids to regulate osteoclast differentiation in mice.

Hu G, Yu Y, Ren Y, Tower RJ, Zhang GF, Karner CM. Hu G, et al. Among authors: tower rj. EMBO Rep. 2024 Oct;25(10):4515-4541. doi: 10.1038/s44319-024-00255-x. Epub 2024 Sep 13. EMBO Rep. 2024. PMID: 39271775 Free PMC article.

10

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair.

Kang H, Strong AL, Sun Y, Guo L, Juan C, Bancroft AC, Choi JH, Pagani CA, Fernandes AA, Woodard M, Lee J, Ramesh S, James AW, Hudson D, Dalby KN, Xu L, Tower RJ, Levi B. Kang H, et al. Among authors: tower rj. Bone Res. 2024 Mar 12;12(1):17. doi: 10.1038/s41413-024-00320-0. Bone Res. 2024. PMID: 38472175 Free PMC article.

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