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Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi.
Bosch-Navarrete C, Pérez-Moreno G, Annang F, Diaz-Gonzalez R, García-Hernández R, Rocha H, Gamarro F, Cordón-Obras C, Navarro M, Rodriguez A, Genilloud O, Reyes F, Vicente F, Ruiz-Pérez LM, González-Pacanowska D. Bosch-Navarrete C, et al. Among authors: rocha h. PLoS Negl Trop Dis. 2023 Sep 15;17(9):e0011592. doi: 10.1371/journal.pntd.0011592. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37713416 Free PMC article.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
Zhan W, Li D, Subramanyaswamy SB, Liu YJ, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H, Sherman J, Qin J, Herring M, Simwela NV, Waters AP, Sukenick G, Cui L, Rodriguez A, Deng H, Nathan CF, Kirkman LA, Lin G. Zhan W, et al. Among authors: rocha h. Cell Chem Biol. 2023 May 18;30(5):457-469.e11. doi: 10.1016/j.chembiol.2023.04.006. Epub 2023 May 5. Cell Chem Biol. 2023. PMID: 37148884 Free PMC article.
Catalyzing sustainable development: insights from the international workshop on STI policies and innovation systems in Central America.
Huete-Pérez JA, Hernández-Mondragón AC, Massey DS, Cumba García LM, Amadei B, De León Sautú N, Acosta ML, Asensio O, Boright J, Cosgrove S, Hernández Hernández E, López-Selva M, Manfredi JL, Mondragón F, Natera JM, Picardo Joao OC, Rivero Santos A, Rocha HO. Huete-Pérez JA, et al. Among authors: rocha ho. Front Res Metr Anal. 2024 Dec 11;9:1511393. doi: 10.3389/frma.2024.1511393. eCollection 2024. Front Res Metr Anal. 2024. PMID: 39722835 Free PMC article.
703 results