Ducho C - Search Results

1

Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity.

Wagdy RA, Abutaleb NS, Fathalla RK, Elgammal Y, Weck S, Pal R, Fischer PD, Ducho C, Abadi AH, N Seleem M, Engel M, Abdel-Halim M. Wagdy RA, et al. Among authors: ducho c. Eur J Med Chem. 2023 Dec 5;261:115789. doi: 10.1016/j.ejmech.2023.115789. Epub 2023 Sep 4. Eur J Med Chem. 2023. PMID: 37717380

2

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

Hamed RB, Mecinović J, Ducho C, Claridge TD, Schofield CJ. Hamed RB, et al. Among authors: ducho c. Chem Commun (Camb). 2010 Mar 7;46(9):1413-5. doi: 10.1039/b924519g. Epub 2010 Jan 12. Chem Commun (Camb). 2010. PMID: 20162132

3

Convergence leads to success: total synthesis of the complex nonribosomal peptide polytheonamide B.

Ducho C. Ducho C. Angew Chem Int Ed Engl. 2010 Jul 12;49(30):5034-6. doi: 10.1002/anie.201001917. Angew Chem Int Ed Engl. 2010. PMID: 20572229 No abstract available.

4

Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity.

Ducho C, Balzarini J, Naesens L, De Clercq E, Meier C. Ducho C, et al. Antivir Chem Chemother. 2002 Mar;13(2):129-41. doi: 10.1177/095632020201300206. Antivir Chem Chemother. 2002. PMID: 12238530 Free article.

5

Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

Ducho C, Hamed RB, Batchelar ET, Sorensen JL, Odell B, Schofield CJ. Ducho C, et al. Org Biomol Chem. 2009 Jul 7;7(13):2770-9. doi: 10.1039/b903312b. Epub 2009 May 11. Org Biomol Chem. 2009. PMID: 19532994

6

Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase.

Ducho C, Jessel S, Gisch N, Balzarini J, Meier C. Ducho C, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):519-22. doi: 10.1081/ncn-200061791. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247982

7

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.

Hamed RB, Gomez-Castellanos JR, Thalhammer A, Harding D, Ducho C, Claridge TD, Schofield CJ. Hamed RB, et al. Among authors: ducho c. Nat Chem. 2011 May;3(5):365-71. doi: 10.1038/nchem.1011. Epub 2011 Apr 3. Nat Chem. 2011. PMID: 21505494

8

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics.

Koppermann S, Cui Z, Fischer PD, Wang X, Ludwig J, Thorson JS, Van Lanen SG, Ducho C. Koppermann S, et al. Among authors: ducho c. ChemMedChem. 2018 Apr 23;13(8):779-784. doi: 10.1002/cmdc.201700793. Epub 2018 Mar 23. ChemMedChem. 2018. PMID: 29438582 Free PMC article.

9

Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors.

El-Sharkawy LY, El-Sakhawy RA, Abdel-Halim M, Lee K, Piazza GA, Ducho C, Hartmann RW, Abadi AH. El-Sharkawy LY, et al. Among authors: ducho c. Arch Pharm (Weinheim). 2018 May;351(5):e1800018. doi: 10.1002/ardp.201800018. Epub 2018 Apr 14. Arch Pharm (Weinheim). 2018. PMID: 29656464

10

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit.

Heib A, Niro G, Weck SC, Koppermann S, Ducho C. Heib A, et al. Among authors: ducho c. Molecules. 2019 Dec 19;25(1):22. doi: 10.3390/molecules25010022. Molecules. 2019. PMID: 31861655 Free PMC article.

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