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Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.
Schlabach MR, Lin S, Collester ZR, Wrocklage C, Shenker S, Calnan C, Xu T, Gannon HS, Williams LJ, Thompson F, Dunbar PR, LaMothe RA, Garrett TE, Colletti N, Hohmann AF, Tubo NJ, Bullock CP, Le Mercier I, Sofjan K, Merkin JJ, Keegan S, Kryukov GV, Dugopolski C, Stegmeier F, Wong K, Sharp FA, Cadzow L, Benson MJ. Schlabach MR, et al. Among authors: lamothe ra. J Clin Invest. 2023 Dec 15;133(24):e163096. doi: 10.1172/JCI163096. J Clin Invest. 2023. PMID: 38099496 Free PMC article.
Detecting Anosognosia from the Prodromal Stage of Alzheimer's Disease.
Guieysse T, Lamothe R, Houot M, Razafimahatratra S, Medani T, Lejeune FX, Dreyfus G, Klarsfeld A, Pantazis D, Koechlin E, Andrade K. Guieysse T, et al. Among authors: lamothe r. J Alzheimers Dis. 2023;95(4):1723-1733. doi: 10.3233/JAD-230552. J Alzheimers Dis. 2023. PMID: 37718816 Free PMC article.
Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability.
Alexander LM, Aliaga Goltsman DS, Liu J, Lin JL, Temoche-Diaz MM, Laperriere SM, Neerincx A, Bednarski C, Knyphausen P, Cohnen A, Albers J, Gonzalez-Osorio L, Fregoso Ocampo R, Oki J, Devoto AE, Castelle CJ, Lamothe RC, Cost GJ, Butterfield CN, Thomas BC, Brown CT. Alexander LM, et al. Among authors: lamothe rc. CRISPR J. 2023 Jun;6(3):261-277. doi: 10.1089/crispr.2022.0090. CRISPR J. 2023. PMID: 37272861 Free PMC article.
Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes.
Aliaga Goltsman DS, Alexander LM, Lin JL, Fregoso Ocampo R, Freeman B, Lamothe RC, Perez Rivas A, Temoche-Diaz MM, Chadha S, Nordenfelt N, Janson OP, Barr I, Devoto AE, Cost GJ, Butterfield CN, Thomas BC, Brown CT. Aliaga Goltsman DS, et al. Among authors: lamothe rc. Nat Commun. 2022 Dec 15;13(1):7602. doi: 10.1038/s41467-022-35257-7. Nat Commun. 2022. PMID: 36522342 Free PMC article.
50 results