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SETD2 safeguards the genome against isochromosome formation.
Mason FM, Kounlavong ES, Tebeje AT, Dahiya R, Guess T, Khan A, Vlach L, Norris SR, Lovejoy CA, Dere R, Strahl BD, Ohi R, Ly P, Walker CL, Rathmell WK. Mason FM, et al. Among authors: ly p. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2303752120. doi: 10.1073/pnas.2303752120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722039 Free PMC article.
Mechanistic origins of diverse genome rearrangements in cancer.
Dahiya R, Hu Q, Ly P. Dahiya R, et al. Among authors: ly p. Semin Cell Dev Biol. 2022 Mar;123:100-109. doi: 10.1016/j.semcdb.2021.03.003. Epub 2021 Apr 3. Semin Cell Dev Biol. 2022. PMID: 33824062 Free PMC article. Review.
Mitotic clustering of pulverized chromosomes from micronuclei.
Lin YF, Hu Q, Mazzagatti A, Valle-Inclán JE, Maurais EG, Dahiya R, Guyer A, Sanders JT, Engel JL, Nguyen G, Bronder D, Bakhoum SF, Cortés-Ciriano I, Ly P. Lin YF, et al. Among authors: ly p. Nature. 2023 Jun;618(7967):1041-1048. doi: 10.1038/s41586-023-05974-0. Epub 2023 May 10. Nature. 2023. PMID: 37165191 Free PMC article.
Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors.
Hu Q, Valle-Inclan JE, Dahiya R, Guyer A, Mazzagatti A, Maurais EG, Engel JL, Cortés-Ciriano I, Ly P. Hu Q, et al. Among authors: ly p. bioRxiv [Preprint]. 2023 Aug 11:2023.08.10.552800. doi: 10.1101/2023.08.10.552800. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 4;15(1):5611. doi: 10.1038/s41467-024-49985-5 PMID: 37609143 Free PMC article. Updated. Preprint.
Epigenetic dysregulation from chromosomal transit in micronuclei.
Agustinus AS, Al-Rawi D, Dameracharla B, Raviram R, Jones BSCL, Stransky S, Scipioni L, Luebeck J, Di Bona M, Norkunaite D, Myers RM, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel PS, Mittal V, Shah SP, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum MF, Koche RP, Sidoli S, Bafna V, David Y, Bakhoum SF. Agustinus AS, et al. Among authors: ly p. Nature. 2023 Jul;619(7968):176-183. doi: 10.1038/s41586-023-06084-7. Epub 2023 Jun 7. Nature. 2023. PMID: 37286593 Free PMC article.
210 results