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KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir.
Astorga-Gamaza A, Perea D, Sanchez-Gaona N, Calvet-Mirabent M, Gallego-Cortés A, Grau-Expósito J, Sanchez-Cerrillo I, Rey J, Castellví J, Curran A, Burgos J, Navarro J, Suanzes P, Falcó V, Genescà M, Martín-Gayo E, Buzon MJ. Astorga-Gamaza A, et al. Among authors: genesca m. Cell Rep Med. 2023 Oct 17;4(10):101202. doi: 10.1016/j.xcrm.2023.101202. Epub 2023 Sep 22. Cell Rep Med. 2023. PMID: 37741278 Free PMC article.
Dextran sulfate from Leuconostoc mesenteroides B512F exerts potent antiviral activity against SARS-CoV-2 in vitro and in vivo.
Andreu S, von Kobbe C, Delgado P, Ripa I, Buzón MJ, Genescà M, Gironès N, Del Moral-Salmoral J, Ramírez GA, Zúñiga S, Enjuanes L, López-Guerrero JA, Bello-Morales R. Andreu S, et al. Among authors: genesca m. Front Microbiol. 2023 May 3;14:1185504. doi: 10.3389/fmicb.2023.1185504. eCollection 2023. Front Microbiol. 2023. PMID: 37206325 Free PMC article.
Targeting HIV persistence in the tissue.
Pieren DKJ, Benítez-Martínez A, Genescà M. Pieren DKJ, et al. Among authors: genesca m. Curr Opin HIV AIDS. 2024 Mar 1;19(2):69-78. doi: 10.1097/COH.0000000000000836. Epub 2024 Jan 8. Curr Opin HIV AIDS. 2024. PMID: 38169333 Review.
Editorial overview: The march of mucosal vaccines.
Lavelle EC, Genescà M. Lavelle EC, et al. Among authors: genesca m. Curr Opin Immunol. 2024 Feb;86:102408. doi: 10.1016/j.coi.2023.102408. Epub 2023 Dec 20. Curr Opin Immunol. 2024. PMID: 38128438 No abstract available.
NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins.
Tsukalov I, Sánchez-Cerrillo I, Rajas O, Avalos E, Iturricastillo G, Esparcia L, Buzón MJ, Genescà M, Scagnetti C, Popova O, Martin-Cófreces N, Calvet-Mirabent M, Marcos-Jimenez A, Martínez-Fleta P, Delgado-Arévalo C, de Los Santos I, Muñoz-Calleja C, Calzada MJ, González Álvaro I, Palacios-Calvo J, Alfranca A, Ancochea J, Sánchez-Madrid F, Martin-Gayo E. Tsukalov I, et al. Among authors: genesca m. Nat Commun. 2024 Mar 7;15(1):2100. doi: 10.1038/s41467-024-46322-8. Nat Commun. 2024. PMID: 38453949 Free PMC article.
Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells.
Kobayashi-Ishihara M, Frazão Smutná K, Alonso FE, Argilaguet J, Esteve-Codina A, Geiger K, Genescà M, Grau-Expósito J, Duran-Castells C, Rogenmoser S, Böttcher R, Jungfleisch J, Oliva B, Martinez JP, Li M, David M, Yamagishi M, Ruiz-Riol M, Brander C, Tsunetsugu-Yokota Y, Buzon MJ, Díez J, Meyerhans A. Kobayashi-Ishihara M, et al. Among authors: genesca m. Commun Biol. 2023 May 10;6(1):487. doi: 10.1038/s42003-023-04841-y. Commun Biol. 2023. PMID: 37165099 Free PMC article.
47 results