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KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir.
Astorga-Gamaza A, Perea D, Sanchez-Gaona N, Calvet-Mirabent M, Gallego-Cortés A, Grau-Expósito J, Sanchez-Cerrillo I, Rey J, Castellví J, Curran A, Burgos J, Navarro J, Suanzes P, Falcó V, Genescà M, Martín-Gayo E, Buzon MJ. Astorga-Gamaza A, et al. Cell Rep Med. 2023 Oct 17;4(10):101202. doi: 10.1016/j.xcrm.2023.101202. Epub 2023 Sep 22. Cell Rep Med. 2023. PMID: 37741278 Free PMC article.
Dendritic Cell Immune Responses in HIV-1 Controllers.
Martin-Gayo E, Yu XG. Martin-Gayo E, et al. Curr HIV/AIDS Rep. 2017 Feb;14(1):1-7. doi: 10.1007/s11904-017-0345-0. Curr HIV/AIDS Rep. 2017. PMID: 28110421 Free PMC article. Review.
HIV-1 persistence in CD4+ T cells with stem cell-like properties.
Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. Buzon MJ, et al. Nat Med. 2014 Feb;20(2):139-42. doi: 10.1038/nm.3445. Epub 2014 Jan 12. Nat Med. 2014. PMID: 24412925 Free PMC article.
Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells.
Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M. Buzon MJ, et al. J Virol. 2014 Sep 1;88(17):10056-65. doi: 10.1128/JVI.01046-14. Epub 2014 Jun 25. J Virol. 2014. PMID: 24965451 Free PMC article.
COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes.
Sánchez-Cerrillo I, Landete P, Aldave B, Sánchez-Alonso S, Sánchez-Azofra A, Marcos-Jiménez A, Ávalos E, Alcaraz-Serna A, de Los Santos I, Mateu-Albero T, Esparcia L, López-Sanz C, Martínez-Fleta P, Gabrie L, Del Campo Guerola L, de la Fuente H, Calzada MJ, González-Álvaro I, Alfranca A, Sánchez-Madrid F, Muñoz-Calleja C, Soriano JB, Ancochea J, Martín-Gayo E; REINMUN-COVID and EDEPIMIC groups. Sánchez-Cerrillo I, et al. J Clin Invest. 2020 Dec 1;130(12):6290-6300. doi: 10.1172/JCI140335. J Clin Invest. 2020. PMID: 32784290 Free PMC article. Clinical Trial.
Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID-19 patients.
Marcos-Jiménez A, Sánchez-Alonso S, Alcaraz-Serna A, Esparcia L, López-Sanz C, Sampedro-Núñez M, Mateu-Albero T, Sánchez-Cerrillo I, Martínez-Fleta P, Gabrie L, Del Campo Guerola L, Rodríguez-Frade JM, Casasnovas JM, Reyburn HT, Valés-Gómez M, López-Trascasa M, Martín-Gayo E, Calzada MJ, Castañeda S, de la Fuente H, González-Álvaro I, Sánchez-Madrid F, Muñoz-Calleja C, Alfranca A. Marcos-Jiménez A, et al. Eur J Immunol. 2021 Mar;51(3):634-647. doi: 10.1002/eji.202048858. Epub 2021 Jan 22. Eur J Immunol. 2021. PMID: 33251605 Free PMC article.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice.
Calvet-Mirabent M, Claiborne DT, Deruaz M, Tanno S, Serra C, Delgado-Arévalo C, Sánchez-Cerrillo I, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Allen TM, Buzón MJ, Balazs A, Vrbanac V, Martín-Gayo E. Calvet-Mirabent M, et al. Eur J Immunol. 2022 Mar;52(3):447-461. doi: 10.1002/eji.202149502. Epub 2022 Jan 8. Eur J Immunol. 2022. PMID: 34935145 Free article.
Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV.
Calvet-Mirabent M, Sánchez-Cerrillo I, Martín-Cófreces N, Martínez-Fleta P, de la Fuente H, Tsukalov I, Delgado-Arévalo C, Calzada MJ, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Buzón MJ, Martín-Gayo E. Calvet-Mirabent M, et al. EBioMedicine. 2022 Jul;81:104090. doi: 10.1016/j.ebiom.2022.104090. Epub 2022 Jun 2. EBioMedicine. 2022. PMID: 35665682 Free PMC article.
49 results