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Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state.
Paryani F, Kwon JS, Ng CW, Madden N, Ofori K, Tang A, Lu H, Li J, Mahajan A, Davidson SM, Basile A, McHugh C, Vonsattel JP, Hickman R, Zody M, Houseman DE, Goldman JE, Yoo AS, Menon V, Al-Dalahmah O. Paryani F, et al. Among authors: mchugh c. bioRxiv [Preprint]. 2023 Sep 12:2023.09.08.556867. doi: 10.1101/2023.09.08.556867. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 8;15(1):6742. doi: 10.1038/s41467-024-50626-0 PMID: 37745577 Free PMC article. Updated. Preprint.
Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state.
Paryani F, Kwon JS, Ng CW, Jakubiak K, Madden N, Ofori K, Tang A, Lu H, Xia S, Li J, Mahajan A, Davidson SM, Basile AO, McHugh C, Vonsattel JP, Hickman R, Zody MC, Housman DE, Goldman JE, Yoo AS, Menon V, Al-Dalahmah O. Paryani F, et al. Among authors: mchugh c. Nat Commun. 2024 Aug 8;15(1):6742. doi: 10.1038/s41467-024-50626-0. Nat Commun. 2024. PMID: 39112488 Free PMC article.
A mystery solved: human high-frequency middle-ear motion.
Nakajima H, McHugh C, Ravicz M, Secchia P, Graf L, Cho NH. Nakajima H, et al. Among authors: mchugh c. Res Sq [Preprint]. 2024 Oct 29:rs.3.rs-5248220. doi: 10.21203/rs.3.rs-5248220/v1. Res Sq. 2024. PMID: 39574904 Free PMC article. Preprint.
Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
Mathews EW, Coffey SR, Gärtner A, Belgrad J, Bragg RM, O'Reilly D, Cantle JP, McHugh C, Summers A, Fentz J, Schwagarus T, Cornelius A, Lingos I, Burch Z, Kovalenko M, Andrew MA, Frank Bennett C, Kordasiewicz HB, Marchionini DM, Wilkinson H, Vogt TF, Pinto RM, Khvorova A, Howland D, Wheeler VC, Carroll JB. Mathews EW, et al. Among authors: mchugh c. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.619693. doi: 10.1101/2024.11.04.619693. bioRxiv. 2024. PMID: 39574582 Free PMC article. Preprint.
The UmboMic: A PVDF Cantilever Microphone.
Yeiser AJ, Wawrzynek EF, Zhang JZ, Graf L, McHugh CI, Kymissis I, Olson ES, Lang JH, Nakajima HH. Yeiser AJ, et al. Among authors: mchugh ci. J Micromech Microeng. 2024 Aug;34(8):085010. doi: 10.1088/1361-6439/ad5c6d. Epub 2024 Jul 18. J Micromech Microeng. 2024. PMID: 39493505
The International Climate Psychology Collaboration: Climate change-related data collected from 63 countries.
Doell KC, Todorova B, Vlasceanu M, Bak Coleman JB, Pronizius E, Schumann P, Azevedo F, Patel Y, Berkebile-Wineberg MM, Brick C, Lange F, Grayson SJ, Pei Y, Chakroff A, van den Broek KL, Lamm C, Vlasceanu D, Constantino SM, Rathje S, Goldwert D, Fang K, Aglioti SM, Alfano M, Alvarado-Yepez AJ, Andersen A, Anseel F, Apps MAJ, Asadli C, Awuor FJ, Basaglia P, Bélanger JJ, Berger S, Bertin P, Białek M, Bialobrzeska O, Blaya-Burgo M, Bleize DNM, Bø S, Boecker L, Boggio PS, Borau S, Borau S, Bos B, Bouguettaya A, Brauer M, Brik T, Briker R, Brosch T, Buchel O, Buonauro D, Butalia R, Carvacho H, Chamberlain SAE, Chan HY, Chow D, Chung D, Cian L, Cohen-Eick N, Contreras-Huerta LS, Contu D, Cristea V, Cutler J, D'Ottone S, De Keersmaecker J, Delcourt S, Delouvée S, Diel K, Douglas BD, Drupp MA, Dubey S, Ekmanis J, Elbaek CT, Elsherif M, Engelhard IM, Escher YA, Etienne TW, Farage L, Farias AR, Feuerriegel S, Findor A, Freira L, Friese M, Gains NP, Gallyamova A, Geiger SJ, Genschow O, Gjoneska B, Gkinopoulos T, Goldberg B, Goldenberg A, Gradidge S, Grassini S, Gray K, Grelle S, Griffin SM, Grigoryan L, Grigoryan A, Grigoryev D, Gruber J, Guilaran J, Hadar B, Hahnel UJJ, Halperin E, Harvey AJ… See abstract for full author list ➔ Doell KC, et al. Among authors: mchugh c. Sci Data. 2024 Oct 1;11(1):1066. doi: 10.1038/s41597-024-03865-1. Sci Data. 2024. PMID: 39353944 Free PMC article.
Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy.
Fontana M, Berk JL, Gillmore JD, Witteles RM, Grogan M, Drachman B, Damy T, Garcia-Pavia P, Taubel J, Solomon SD, Sheikh FH, Tahara N, González-Costello J, Tsujita K, Morbach C, Pozsonyi Z, Petrie MC, Delgado D, Van der Meer P, Jabbour A, Bondue A, Kim D, Azevedo O, Hvitfeldt Poulsen S, Yilmaz A, Jankowska EA, Algalarrondo V, Slugg A, Garg PP, Boyle KL, Yureneva E, Silliman N, Yang L, Chen J, Eraly SA, Vest J, Maurer MS; HELIOS-B Trial Investigators. Fontana M, et al. N Engl J Med. 2024 Aug 30. doi: 10.1056/NEJMoa2409134. Online ahead of print. N Engl J Med. 2024. PMID: 39213194
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.
Pero JE, Mueller EA, Adams AM, Adolph RS, Bagchi P, Balce D, Bantscheff M, Barauskas O, Bartha I, Bohan D, Cai H, Carabajal E, Cassidy J, Cato M, Chaudhary KW, Chen D, Chen YP, Colas C, Darwech I, Eberl HC, Fernandez B, Gordon E, Grosse J, Hansen J, Hetzler B, Hwang S, Jeyasingh S, Kowalski B, Lehmann S, Lo G, McAllaster M, McHugh C, Momont C, Newby Z, Nigro M, Oladunni F, Pannirselvam M, Park A, Pearson N, Peat AJ, Plastridge B, Ranjan R, Safabakhsh P, Shapiro ND, Soriaga L, Stokes N, Sweeney D, Talecki L, Telenti A, Terrell A, Tse W, Wang L, Wang S, Wedel L, Werner T, Dalmas Wilk D, Yim S, Zhou J. Pero JE, et al. Among authors: mchugh c. J Med Chem. 2024 Aug 22;67(16):14586-14608. doi: 10.1021/acs.jmedchem.4c01402. Epub 2024 Aug 13. J Med Chem. 2024. PMID: 39136957
321 results