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Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state.
Paryani F, Kwon JS, Ng CW, Madden N, Ofori K, Tang A, Lu H, Li J, Mahajan A, Davidson SM, Basile A, McHugh C, Vonsattel JP, Hickman R, Zody M, Houseman DE, Goldman JE, Yoo AS, Menon V, Al-Dalahmah O. Paryani F, et al. Among authors: tang a. bioRxiv [Preprint]. 2023 Sep 12:2023.09.08.556867. doi: 10.1101/2023.09.08.556867. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 8;15(1):6742. doi: 10.1038/s41467-024-50626-0 PMID: 37745577 Free PMC article. Updated. Preprint.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM. Lim RG, et al. Among authors: tang g, tang a. Nat Commun. 2022 Dec 21;13(1):7791. doi: 10.1038/s41467-022-35388-x. Nat Commun. 2022. PMID: 36543778 Free PMC article.
Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state.
Paryani F, Kwon JS, Ng CW, Jakubiak K, Madden N, Ofori K, Tang A, Lu H, Xia S, Li J, Mahajan A, Davidson SM, Basile AO, McHugh C, Vonsattel JP, Hickman R, Zody MC, Housman DE, Goldman JE, Yoo AS, Menon V, Al-Dalahmah O. Paryani F, et al. Among authors: tang a. Nat Commun. 2024 Aug 8;15(1):6742. doi: 10.1038/s41467-024-50626-0. Nat Commun. 2024. PMID: 39112488 Free PMC article.
A non-canonical striatopallidal Go pathway that supports motor control.
Labouesse MA, Torres-Herraez A, Chohan MO, Villarin JM, Greenwald J, Sun X, Zahran M, Tang A, Lam S, Veenstra-VanderWeele J, Lacefield CO, Bonaventura J, Michaelides M, Chan CS, Yizhar O, Kellendonk C. Labouesse MA, et al. Among authors: tang a. Nat Commun. 2023 Oct 23;14(1):6712. doi: 10.1038/s41467-023-42288-1. Nat Commun. 2023. PMID: 37872145 Free PMC article.
Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease.
Li Y, Serras CP, Blumenfeld J, Xie M, Hao Y, Deng E, Chun YY, Holtzman J, An A, Yoon SY, Tang X, Rao A, Woldemariam S, Tang A, Zhang A, Simms J, Lo I, Oskotsky T, Keiser MJ, Huang Y, Sirota M. Li Y, et al. Among authors: tang a. bioRxiv [Preprint]. 2024 Dec 13:2024.12.09.627436. doi: 10.1101/2024.12.09.627436. bioRxiv. 2024. PMID: 39713353 Free PMC article. Preprint.
3,792 results