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Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk.
Ying P, Chen C, Lu Z, Chen S, Zhang M, Cai Y, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Tian W, Yang Z, Liu J, Huang C, Yang X, Xu B, Li H, Zhu X, Li N, Li B, Wei Y, Zhu Y, Tian J, Miao X. Ying P, et al. Among authors: fan l. Nat Commun. 2023 Sep 25;14(1):5958. doi: 10.1038/s41467-023-41690-z. Nat Commun. 2023. PMID: 37749132 Free PMC article.
Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk.
Tian J, Chen C, Rao M, Zhang M, Lu Z, Cai Y, Ying P, Li B, Wang H, Wang L, Li Y, Huang J, Fan L, Cai X, Ning C, Li Y, Zhang F, Wang W, Jiang Y, Liu Y, Wang M, Li H, Huang C, Yang Z, Chang J, Zhu Y, Yang X, Miao X. Tian J, et al. Among authors: fan l. Cancer Res. 2022 Jun 6;82(11):2084-2096. doi: 10.1158/0008-5472.CAN-21-4367. Cancer Res. 2022. PMID: 35363263
Pan-Cancer Analysis of Microbiome Quantitative Trait Loci.
Chen C, Cai Y, Liu Y, Chen S, Li Y, Zhang F, Zhang M, Lu Z, Ying P, Huang J, Fan L, Cai X, Ning C, Wang W, Jiang Y, Zhang H, Yang S, Wang Z, Wang X, Zhang S, Huang C, Xu B, Fu Z, Song Q, Jin M, Chen K, Chen H, Dai M, Miao X, Yang X, Zhu Y, Tian J. Chen C, et al. Among authors: fan l. Cancer Res. 2022 Oct 4;82(19):3449-3456. doi: 10.1158/0008-5472.CAN-22-1854. Cancer Res. 2022. PMID: 35972351
HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction.
Lu Z, Fan L, Zhang F, Huang C, Cai Y, Chen C, Li G, Zhang M, Huang J, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Ye T, Liu J, Yang X, Xu B, Zhu Y, Zhong R, Li H, Tian J, Li B, Miao X. Lu Z, et al. Among authors: fan l. Arch Toxicol. 2023 Jul;97(7):2015-2028. doi: 10.1007/s00204-023-03494-4. Epub 2023 May 28. Arch Toxicol. 2023. PMID: 37245169
Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms.
Zhang M, Chen C, Lu Z, Cai Y, Li Y, Zhang F, Liu Y, Chen S, Zhang H, Yang S, Gen H, Jiang Y, Ning C, Huang J, Wang W, Fan L, Zhang Y, Jin M, Han J, Xiong Z, Cai M, Liu J, Huang C, Yang X, Xu B, Li H, Li B, Zhu X, Wei Y, Zhu Y, Tian J, Miao X. Zhang M, et al. Among authors: fan l. Gastroenterology. 2023 Nov;165(5):1151-1167. doi: 10.1053/j.gastro.2023.07.019. Epub 2023 Aug 3. Gastroenterology. 2023. PMID: 37541527
Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci.
Li B, Cai Y, Chen C, Li G, Zhang M, Lu Z, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Zhu Z, Xu B, Li H, Li H, Jin M, Wang X, Zhang S, Liu J, Huang C, Yang X, Wei Y, Zhu Y, Tian J, Miao X. Li B, et al. Among authors: fan l. Cancer Res. 2023 Nov 1;83(21):3650-3666. doi: 10.1158/0008-5472.CAN-23-0251. Cancer Res. 2023. PMID: 37669142
10,130 results
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