Mitchell TA - Search Results

1

Net Intermolecular Silyloxypyrone-Based (5+2) Cycloadditions Utilizing Amides as Enabling and Cleavable Tethers.

Angles SN, Guo W, Darko K, Erzuah M, Pauley KG, Promise IE, Goodell JR, Tantillo DJ, Mitchell TA. Angles SN, et al. Among authors: mitchell ta. Org Lett. 2023 Oct 6;25(39):7137-7141. doi: 10.1021/acs.orglett.3c02635. Epub 2023 Sep 26. Org Lett. 2023. PMID: 37750489

2

Investigation of Transfer Group, Tether Proximity, and Alkene Substitution for Intramolecular Silyloxypyrone-Based [5 + 2] Cycloadditions.

Bulandr JJ, Grabowski JP, Law CM, Shaw JL, Goodell JR, Mitchell TA. Bulandr JJ, et al. Among authors: mitchell ta. J Org Chem. 2019 Aug 16;84(16):10306-10320. doi: 10.1021/acs.joc.9b01479. Epub 2019 Aug 1. J Org Chem. 2019. PMID: 31322900

3

Experimental and Theoretical Investigation of the Synchronicity of Ambident Silyloxypyrone-Based (5 + 2) Cycloadditions.

Youman AJ, Rokey SN, Grabowski JP, Guo W, Sun Q, Angles SN, Goodell JR, Tantillo DJ, Mitchell TA. Youman AJ, et al. Among authors: mitchell ta. J Org Chem. 2023 May 5;88(9):5972-5981. doi: 10.1021/acs.joc.3c00318. Epub 2023 Apr 14. J Org Chem. 2023. PMID: 37058120

4

Unique reactivity of anti- and syn-acetoxypyranones en route to oxidopyrylium intermediates leading to a cascade process.

Woodall EL, Simanis JA, Hamaker CG, Goodell JR, Mitchell TA. Woodall EL, et al. Among authors: mitchell ta. Org Lett. 2013 Jul 5;15(13):3270-3. doi: 10.1021/ol4012986. Epub 2013 Jun 21. Org Lett. 2013. PMID: 23790080

5

Oxidopyrylium-Alkene [5 + 2] Cycloaddition Conjugate Addition Cascade (C³) Sequences: Scope, Limitation, and Computational Investigations.

Kaufman RH, Law CM, Simanis JA, Woodall EL, Zwick CR 3rd, Wedler HB, Wendelboe P, Hamaker CG, Goodell JR, Tantillo DJ, Mitchell TA. Kaufman RH, et al. Among authors: mitchell ta. J Org Chem. 2018 Sep 7;83(17):9818-9838. doi: 10.1021/acs.joc.8b01322. Epub 2018 Jul 26. J Org Chem. 2018. PMID: 30001484

6

Investigation of oxidopyrylium-alkene [5+2] cycloaddition conjugate addition cascade (C3) sequences.

Simanis JA, Law CM, Woodall EL, Hamaker CG, Goodell JR, Mitchell TA. Simanis JA, et al. Among authors: mitchell ta. Chem Commun (Camb). 2014 Aug 21;50(65):9130-3. doi: 10.1039/c4cc04163a. Chem Commun (Camb). 2014. PMID: 24990799

7

Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process.

Mitchell TA, Zhao C, Romo D. Mitchell TA, et al. J Org Chem. 2008 Dec 19;73(24):9544-51. doi: 10.1021/jo801604k. J Org Chem. 2008. PMID: 19053579 Free PMC article.

8

Mechanistic investigations of the ZnCl2-mediated tandem Mukaiyama aldol lactonization: evidence for asynchronous, concerted transition states and discovery of 2-oxopyridyl ketene acetal variants.

Zhao C, Mitchell TA, Vallakati R, Pérez LM, Romo D. Zhao C, et al. Among authors: mitchell ta. J Am Chem Soc. 2012 Feb 15;134(6):3084-94. doi: 10.1021/ja209163w. Epub 2012 Feb 2. J Am Chem Soc. 2012. PMID: 22239064

9

Synthesis of Polycyclic Ether-Benzopyrans and In Vitro Inhibitory Activity against Leishmania tarentolae.

Singh S, Grabowski JP, Pohani S, Apuzzo CF, Platt DC, Jones MA, Mitchell TA. Singh S, et al. Among authors: mitchell ta. Molecules. 2020 Nov 21;25(22):5461. doi: 10.3390/molecules25225461. Molecules. 2020. PMID: 33233418 Free PMC article.

10

Diastereoselective synthesis of tetrahydrofurans via mead reductive cyclization of keto-beta-lactones derived from the tandem Mukaiyama aldol lactonization (TMAL) process.

Mitchell TA, Romo D. Mitchell TA, et al. J Org Chem. 2007 Nov 23;72(24):9053-9. doi: 10.1021/jo7014246. Epub 2007 Nov 1. J Org Chem. 2007. PMID: 17973527 Free PMC article.

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