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Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning.
Höhn J, Krieghoff-Henning E, Wies C, Kiehl L, Hetz MJ, Bucher TC, Jonnagaddala J, Zatloukal K, Müller H, Plass M, Jungwirth E, Gaiser T, Steeg M, Holland-Letz T, Brenner H, Hoffmeister M, Brinker TJ. Höhn J, et al. Among authors: brenner h. NPJ Precis Oncol. 2023 Sep 26;7(1):98. doi: 10.1038/s41698-023-00451-3. NPJ Precis Oncol. 2023. PMID: 37752266 Free PMC article.
Learning high-order interactions for polygenic risk prediction.
Massi MC, Franco NR, Manzoni A, Paganoni AM, Park HA, Hoffmeister M, Brenner H, Chang-Claude J, Ieva F, Zunino P. Massi MC, et al. Among authors: brenner h. PLoS One. 2023 Feb 10;18(2):e0281618. doi: 10.1371/journal.pone.0281618. eCollection 2023. PLoS One. 2023. PMID: 36763605 Free PMC article.
Bovine meat and milk factor protein expression in tumor-free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival.
Nikitina E, Burk-Körner A, Wiesenfarth M, Alwers E, Heide D, Tessmer C, Ernst C, Krunic D, Schrotz-King P, Chang-Claude J, von Winterfeld M, Herpel E, Brobeil A, Brenner H, Heikenwalder M, Hoffmeister M, Kopp-Schneider A, Bund T. Nikitina E, et al. Among authors: brenner h. Mol Oncol. 2024 May;18(5):1076-1092. doi: 10.1002/1878-0261.13390. Epub 2023 Feb 22. Mol Oncol. 2024. PMID: 36811271 Free PMC article.
Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.
Georgeson P, Steinfelder RS, Harrison TA, Pope BJ, Zaidi SH, Qu C, Lin Y, Joo JE, Mahmood K, Clendenning M, Walker R, Aglago EK, Berndt SI, Brenner H, Campbell PT, Cao Y, Chan AT, Chang-Claude J, Dimou N, Doheny KF, Drew DA, Figueiredo JC, French AJ, Gallinger S, Giannakis M, Giles GG, Goode EL, Gruber SB, Gsur A, Gunter MJ, Harlid S, Hoffmeister M, Hsu L, Huang WY, Huyghe JR, Manson JE, Moreno V, Murphy N, Nassir R, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Pai RK, Papadimitrou N, Potter JD, Schoen RE, Song M, Sun W, Toland AE, Trinh QM, Tsilidis K, Ugai T, Um CY, Macrae FA, Rosty C, Hudson TJ, Winship IM, Phipps AI, Jenkins MA, Peters U, Buchanan DD. Georgeson P, et al. Among authors: brenner h. medRxiv [Preprint]. 2024 Jan 30:2023.03.10.23287127. doi: 10.1101/2023.03.10.23287127. medRxiv. 2024. PMID: 37090539 Free PMC article. Preprint.
2,449 results