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Page 1
Independent effects of testosterone, estradiol, and sex chromosomes on gene expression in immune cells of trans- and cisgender individuals.
Harris RM, Whitfield T, Blanton LV, Skaletsky H, Blumen K, Hyland P, McDermott E, Summers K, Hughes JF, Jackson E, Teglas P, Liu B, Chan YM, Page DC. Harris RM, et al. Among authors: hughes jf. bioRxiv [Preprint]. 2024 Oct 9:2024.10.08.617275. doi: 10.1101/2024.10.08.617275. bioRxiv. 2024. PMID: 39416170 Free PMC article. Preprint.
Where is the boundary of the human pseudoautosomal region?
Bellott DW, Hughes JF, Skaletsky H, Owen EC, Page DC. Bellott DW, et al. Among authors: hughes jf. Am J Hum Genet. 2024 Nov 7;111(11):2530-2541. doi: 10.1016/j.ajhg.2024.09.005. Epub 2024 Oct 14. Am J Hum Genet. 2024. PMID: 39406244 Free PMC article.
Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types.
Blanton LV, San Roman AK, Wood G, Buscetta A, Banks N, Skaletsky H, Godfrey AK, Pham TT, Hughes JF, Brown LG, Kruszka P, Lin AE, Kastner DL, Muenke M, Page DC. Blanton LV, et al. Among authors: hughes jf. Cell Genom. 2024 Sep 11;4(9):100628. doi: 10.1016/j.xgen.2024.100628. Epub 2024 Aug 6. Cell Genom. 2024. PMID: 39111319 Free PMC article.
Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types.
Blanton LV, San Roman AK, Wood G, Buscetta A, Banks N, Skaletsky H, Godfrey AK, Pham TT, Hughes JF, Brown LG, Kruszka P, Lin AE, Kastner DL, Muenke M, Page DC. Blanton LV, et al. Among authors: hughes jf. bioRxiv [Preprint]. 2024 Mar 19:2024.03.18.585578. doi: 10.1101/2024.03.18.585578. bioRxiv. 2024. Update in: Cell Genom. 2024 Sep 11;4(9):100628. doi: 10.1016/j.xgen.2024.100628 PMID: 38562807 Free PMC article. Updated. Preprint.
The human Y and inactive X chromosomes similarly modulate autosomal gene expression.
San Roman AK, Skaletsky H, Godfrey AK, Bokil NV, Teitz L, Singh I, Blanton LV, Bellott DW, Pyntikova T, Lange J, Koutseva N, Hughes JF, Brown L, Phou S, Buscetta A, Kruszka P, Banks N, Dutra A, Pak E, Lasutschinkow PC, Keen C, Davis SM, Lin AE, Tartaglia NR, Samango-Sprouse C, Muenke M, Page DC. San Roman AK, et al. Among authors: hughes jf. Cell Genom. 2024 Jan 10;4(1):100462. doi: 10.1016/j.xgen.2023.100462. Epub 2023 Dec 13. Cell Genom. 2024. PMID: 38190107 Free PMC article.
Human microglia maturation is underpinned by specific gene regulatory networks.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA; Birth Defects Research Laboratory; Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. Han CZ, et al. Among authors: hughes jf. Immunity. 2023 Sep 12;56(9):2152-2171.e13. doi: 10.1016/j.immuni.2023.07.016. Epub 2023 Aug 14. Immunity. 2023. PMID: 37582369 Free PMC article.
The human Y and inactive X chromosomes similarly modulate autosomal gene expression.
San Roman AK, Skaletsky H, Godfrey AK, Bokil NV, Teitz L, Singh I, Blanton LV, Bellott DW, Pyntikova T, Lange J, Koutseva N, Hughes JF, Brown L, Phou S, Buscetta A, Kruszka P, Banks N, Dutra A, Pak E, Lasutschinkow PC, Keen C, Davis SM, Lin AE, Tartaglia NR, Samango-Sprouse C, Muenke M, Page DC. San Roman AK, et al. Among authors: hughes jf. bioRxiv [Preprint]. 2023 Jun 7:2023.06.05.543763. doi: 10.1101/2023.06.05.543763. bioRxiv. 2023. Update in: Cell Genom. 2024 Jan 10;4(1):100462. doi: 10.1016/j.xgen.2023.100462 PMID: 37333288 Free PMC article. Updated. Preprint.
The human inactive X chromosome modulates expression of the active X chromosome.
San Roman AK, Godfrey AK, Skaletsky H, Bellott DW, Groff AF, Harris HL, Blanton LV, Hughes JF, Brown L, Phou S, Buscetta A, Kruszka P, Banks N, Dutra A, Pak E, Lasutschinkow PC, Keen C, Davis SM, Tartaglia NR, Samango-Sprouse C, Muenke M, Page DC. San Roman AK, et al. Among authors: hughes jf. Cell Genom. 2023 Feb 8;3(2):100259. doi: 10.1016/j.xgen.2023.100259. eCollection 2023 Feb 8. Cell Genom. 2023. PMID: 36819663 Free PMC article.
61 results