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Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum.
Popoli P, Pintor A, Domenici MR, Frank C, Tebano MT, Pèzzola A, Scarchilli L, Quarta D, Reggio R, Malchiodi-Albedi F, Falchi M, Massotti M. Popoli P, et al. J Neurosci. 2002 Mar 1;22(5):1967-75. doi: 10.1523/JNEUROSCI.22-05-01967.2002. J Neurosci. 2002. PMID: 11880527 Free PMC article.
Metabotropic glutamate receptor 5 (mGluR5)-mediated phosphoinositide hydrolysis and NMDA-potentiating effects are blunted in the striatum of aged rats: a possible additional mechanism in striatal senescence.
Domenici MR, Pintor A, Potenza RL, Gaudi S, Grò MC, Passarelli F, Reggio R, Galluzzo M, Massotti M, Popoli P. Domenici MR, et al. Among authors: popoli p. Eur J Neurosci. 2003 May;17(10):2047-55. doi: 10.1046/j.1460-9568.2003.02649.x. Eur J Neurosci. 2003. PMID: 12786971
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.
Popoli P, Pintor A, Tebano MT, Frank C, Pepponi R, Nazzicone V, Grieco R, Pèzzola A, Reggio R, Minghetti L, De Berardinis MA, Martire A, Potenza RL, Domenici MR, Massotti M. Popoli P, et al. J Neurochem. 2004 Jun;89(6):1479-89. doi: 10.1111/j.1471-4159.2004.02448.x. J Neurochem. 2004. PMID: 15189351 Free article.
170 results