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Page 1
Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue.
Zhong Z, Chen Y, Deswarte K, Lauwers H, De Lombaerde E, Cui X, Van Herck S, Ye T, Gontsarik M, Lienenklaus S, Sanders NN, Lambrecht BN, De Koker S, De Geest BG. Zhong Z, et al. Among authors: sanders nn. Adv Healthc Mater. 2023 Dec;12(32):e2301687. doi: 10.1002/adhm.202301687. Epub 2023 Oct 11. Adv Healthc Mater. 2023. PMID: 37772637
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot A, Jangra S, Laghlali G, Warang P, Singh G, Chang LA, Park SC, Singh G, De Swarte K, Zhong Z, Louage B, De Lombaerde E, Ye T, Chen Y, Cuadrado-Castano S, Lienenklaus S, Sanders NN, Lambrecht BN, García-Sastre A, Schotsaert M, De Geest BG. Lamoot A, et al. Among authors: sanders nn. Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22. Small. 2024. PMID: 37867244 Free PMC article.
CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity.
Ye T, Zhong Z, Cappellesso F, Deswarte K, Chen Y, Lauwers H, De Lombaerde E, Gontsarik M, Lienenklaus S, Van Lysebetten D, Sanders NN, Lambrecht BN, De Koker S, Laoui D, De Geest BG. Ye T, et al. Among authors: sanders nn. Biomaterials. 2024 Dec;311:122693. doi: 10.1016/j.biomaterials.2024.122693. Epub 2024 Jun 27. Biomaterials. 2024. PMID: 38996672
A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity.
Zhong Z, Deventer MH, Chen Y, Vanhee S, Lammens I, Deswarte K, Huang Y, Ye T, Wang H, Nuhn L, Vandeputte MM, Gontsarik M, Cui X, Sanders NN, Lienenklaus S, N Lambrecht B, Baptista AP, Stove CP, G De Geest B. Zhong Z, et al. Among authors: sanders nn. Angew Chem Int Ed Engl. 2024 Oct 23:e202419031. doi: 10.1002/anie.202419031. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39441822
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models.
Salembier R, De Haes C, Bellemans J, Demeyere K, Van Den Broeck W, Sanders NN, Van Laere S, Lyons TR, Meyer E, Steenbrugge J. Salembier R, et al. Among authors: sanders nn. Breast Cancer Res. 2024 Apr 11;26(1):63. doi: 10.1186/s13058-024-01815-8. Breast Cancer Res. 2024. PMID: 38605414 Free PMC article.
The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Vanderhaeghen T, Timmermans S, Eggermont M, Watts D, Vandewalle J, Wallaeys C, Nuyttens L, De Temmerman J, Hochepied T, Dewaele S, Berghe JV, Sanders N, Wielockx B, Beyaert R, Libert C. Vanderhaeghen T, et al. Front Immunol. 2023 Mar 16;14:1124011. doi: 10.3389/fimmu.2023.1124011. eCollection 2023. Front Immunol. 2023. PMID: 37006237 Free PMC article.
Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation.
De Lombaerde E, Cui X, Chen Y, Zhong Z, Deckers J, Mencarelli G, Opsomer L, Wang H, De Baere J, Lienenklaus S, Lambrecht BN, Sanders NN, De Geest BG. De Lombaerde E, et al. Among authors: sanders nn. ACS Nano. 2024 Oct 15;18(41):28311-28324. doi: 10.1021/acsnano.4c09677. Epub 2024 Oct 1. ACS Nano. 2024. PMID: 39352021
PH-Triggered, Lymph Node Focused Immunodrug Release by Polymeric 2-Propionic-3-Methyl-maleic Anhydrides with Cholesteryl End Groups.
Heck AG, Medina-Montano C, Zhong Z, Deswarte K, Eigen K, Stickdorn J, Kockelmann J, Scherger M, Sanders NN, Lienenklaus S, Lambrecht BN, Grabbe S, De Geest BG, Nuhn L. Heck AG, et al. Among authors: sanders nn. Adv Healthc Mater. 2024 Dec;13(32):e2402875. doi: 10.1002/adhm.202402875. Epub 2024 Sep 23. Adv Healthc Mater. 2024. PMID: 39313985 Free PMC article.
125 results