Zhang W - Search Results

1

Berberine-silybin salt achieves improved anti-nonalcoholic fatty liver disease effect through regulating lipid metabolism.

Ma X, Yu X, Li R, Cui J, Yu H, Ren L, Jiang J, Zhang W, Wang L. Ma X, et al. Among authors: zhang w. J Ethnopharmacol. 2024 Jan 30;319(Pt 2):117238. doi: 10.1016/j.jep.2023.117238. Epub 2023 Sep 27. J Ethnopharmacol. 2024. PMID: 37774895

2

Machine learning- and structure-based discovery of a novel chemotype as FXR agonists for potential treatment of nonalcoholic fatty liver disease.

Qin T, Gao X, Lei L, Feng J, Zhang W, Hu Y, Shen Z, Liu Z, Huan Y, Wu S, Xia J, Zhang L. Qin T, et al. Among authors: zhang l, zhang w. Eur J Med Chem. 2023 Apr 5;252:115307. doi: 10.1016/j.ejmech.2023.115307. Epub 2023 Mar 27. Eur J Med Chem. 2023. PMID: 37003047

3

Structural optimization and biological evaluation of 1-adamantylcarbonyl-4-phenylpiperazine derivatives as FXR agonists for NAFLD.

Qin T, Gao X, Lei L, Zhang W, Feng J, Wang X, Shen Z, Liu Z, Huan Y, Wu S, Xia J, Zhang L. Qin T, et al. Among authors: zhang l, zhang w. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114903. doi: 10.1016/j.ejmech.2022.114903. Epub 2022 Nov 8. Eur J Med Chem. 2023. PMID: 36375336

4

Potent salinomycin C20-O-alkyl oxime derivative SAL-98 efficiently inhibits tumor growth and metastasis by affecting Wnt/β-catenin signal pathway.

Tang L, Duan W, Zhang C, Shi Y, Tu W, Lei K, Zhang W, Wu S, Zhang J. Tang L, et al. Among authors: zhang c, zhang w, zhang j. Biochem Pharmacol. 2023 Aug;214:115666. doi: 10.1016/j.bcp.2023.115666. Epub 2023 Jun 29. Biochem Pharmacol. 2023. PMID: 37391086

5

Discovery of isatin-β-methyldithiocarbazate derivatives as New Delhi metallo- β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates.

Lv H, Zhu Z, Qian C, Li T, Han Z, Zhang W, Si X, Wang J, Deng X, Li L, Fang T, Xia J, Wu S, Zhou Y. Lv H, et al. Among authors: zhang w. Biomed Pharmacother. 2023 Oct;166:115439. doi: 10.1016/j.biopha.2023.115439. Epub 2023 Sep 8. Biomed Pharmacother. 2023. PMID: 37673020 Free article.

6

Novel pleuromutilin derivatives conjugated with phenyl-sulfide and boron-containing moieties as potent antibacterial agents against antibiotic-resistant bacteria.

Luo X, Wu G, Feng J, Zhang J, Fu H, Yu H, Han Z, Nie W, Zhu Z, Liu B, Pan W, Li B, Wang Y, Zhang C, Li T, Zhang W, Wu S. Luo X, et al. Among authors: zhang c, zhang w, zhang j. Eur J Med Chem. 2024 Nov 5;277:116745. doi: 10.1016/j.ejmech.2024.116745. Epub 2024 Aug 3. Eur J Med Chem. 2024. PMID: 39106659

7

Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection.

Zhao X, Feng J, Zhang J, Han Z, Hu Y, Shao HH, Li T, Xia J, Lei K, Wang W, Lai F, Lin Y, Liu B, Zhang K, Zhang C, Yang Q, Luo X, Zhang H, Li C, Zhang W, Wu S. Zhao X, et al. Among authors: zhang c, zhang w, zhang j, zhang k, zhang h. Acta Pharm Sin B. 2023 Dec;13(12):4945-4962. doi: 10.1016/j.apsb.2023.08.030. Epub 2023 Sep 9. Acta Pharm Sin B. 2023. PMID: 38045053 Free PMC article.

8

Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers.

Yang Q, Qin T, An T, Wu H, Xu G, Xiang J, Lei K, Zhang S, Xia J, Su G, Wang D, Xue M, Kong L, Zhang W, Wu S, Li Y. Yang Q, et al. Among authors: zhang s, zhang w. Eur J Pharmacol. 2023 Apr 15;945:175628. doi: 10.1016/j.ejphar.2023.175628. Epub 2023 Feb 28. Eur J Pharmacol. 2023. PMID: 36858339

9

Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection.

Zhang G, Liang J, Wen G, Yao M, Jia Y, Feng B, Li J, Han Z, Liu Q, Li T, Zhang W, Jin H, Xia J, Peng L, Wu S. Zhang G, et al. Among authors: zhang w. Eur J Med Chem. 2024 Sep 28;280:116905. doi: 10.1016/j.ejmech.2024.116905. Online ahead of print. Eur J Med Chem. 2024. PMID: 39368263

10

Identification and Characterization of Two New 1- O-Acyl-glucose-ester Forming Glucosyltransferases from Erigeron breviscapus.

Yang Y, Liu M, Zhang W, Cao Y, Li C, Wang W. Yang Y, et al. Among authors: zhang w. J Agric Food Chem. 2019 Mar 13;67(10):2848-2855. doi: 10.1021/acs.jafc.8b07215. Epub 2019 Mar 1. J Agric Food Chem. 2019. PMID: 30821967

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