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Page 1
Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.
Nies AT, König J, Leuthold P, Damme K, Winter S, Haag M, Masuda S, Kruck S, Daniel H, Spanier B, Fromm MF, Bedke J, Inui KI, Schwab M, Schaeffeler E. Nies AT, et al. Among authors: fromm mf. Pharmacol Res. 2023 Oct;196:106941. doi: 10.1016/j.phrs.2023.106941. Epub 2023 Sep 27. Pharmacol Res. 2023. PMID: 37775020 Free article.
Genetic polymorphisms of the human MDR1 drug transporter.
Schwab M, Eichelbaum M, Fromm MF. Schwab M, et al. Among authors: fromm mf. Annu Rev Pharmacol Toxicol. 2003;43:285-307. doi: 10.1146/annurev.pharmtox.43.100901.140233. Epub 2002 Jan 10. Annu Rev Pharmacol Toxicol. 2003. PMID: 12359865 Review.
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).
Niemi M, Schaeffeler E, Lang T, Fromm MF, Neuvonen M, Kyrklund C, Backman JT, Kerb R, Schwab M, Neuvonen PJ, Eichelbaum M, Kivistö KT. Niemi M, et al. Among authors: fromm mf. Pharmacogenetics. 2004 Jul;14(7):429-40. doi: 10.1097/01.fpc.0000114750.08559.32. Pharmacogenetics. 2004. PMID: 15226675
Clinical aspects of the MDR1 (ABCB1) gene polymorphism.
Eichelbaum M, Fromm MF, Schwab M. Eichelbaum M, et al. Among authors: fromm mf. Ther Drug Monit. 2004 Apr;26(2):180-5. doi: 10.1097/00007691-200404000-00017. Ther Drug Monit. 2004. PMID: 15228162 Review.
Lipid-lowering response to statins is affected by CYP3A5 polymorphism.
Kivistö KT, Niemi M, Schaeffeler E, Pitkälä K, Tilvis R, Fromm MF, Schwab M, Eichelbaum M, Strandberg T. Kivistö KT, et al. Among authors: fromm mf. Pharmacogenetics. 2004 Aug;14(8):523-5. doi: 10.1097/01.fpc.0000114762.78957.a5. Pharmacogenetics. 2004. PMID: 15284534
Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.
Kivistö KT, Zukunft J, Hofmann U, Niemi M, Rekersbrink S, Schneider S, Luippold G, Schwab M, Eichelbaum M, Fromm MF. Kivistö KT, et al. Among authors: fromm mf. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):124-30. doi: 10.1007/s00210-004-0948-z. Epub 2004 Jul 30. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15322734
228 results