Schaeffeler E - Search Results

1

Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.

Nies AT, König J, Leuthold P, Damme K, Winter S, Haag M, Masuda S, Kruck S, Daniel H, Spanier B, Fromm MF, Bedke J, Inui KI, Schwab M, Schaeffeler E. Nies AT, et al. Among authors: schaeffeler e. Pharmacol Res. 2023 Oct;196:106941. doi: 10.1016/j.phrs.2023.106941. Epub 2023 Sep 27. Pharmacol Res. 2023. PMID: 37775020 Free article.

2

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

3

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2002 May;53(5):526-34. doi: 10.1046/j.1365-2125.2002.01591.x. Br J Clin Pharmacol. 2002. PMID: 11994059 Free PMC article. Clinical Trial.

4

Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease.

Furuno T, Landi MT, Ceroni M, Caporaso N, Bernucci I, Nappi G, Martignoni E, Schaeffeler E, Eichelbaum M, Schwab M, Zanger UM. Furuno T, et al. Among authors: schaeffeler e. Pharmacogenetics. 2002 Oct;12(7):529-34. doi: 10.1097/00008571-200210000-00004. Pharmacogenetics. 2002. PMID: 12360103

5

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.

Schwab M, Schaeffeler E, Marx C, Fromm MF, Kaskas B, Metzler J, Stange E, Herfarth H, Schoelmerich J, Gregor M, Walker S, Cascorbi I, Roots I, Brinkmann U, Zanger UM, Eichelbaum M. Schwab M, et al. Among authors: schaeffeler e. Gastroenterology. 2003 Jan;124(1):26-33. doi: 10.1053/gast.2003.50010. Gastroenterology. 2003. PMID: 12512026

6

[Therapy of chronic inflammatory bowel diseases with azathioprine, 6-mercaptopurine and 6-thioguanine. Clinico-pharmacologic aspects].

Schwab M, Herrlinger K, Schaeffeler E, Stange EF. Schwab M, et al. Among authors: schaeffeler e. Dtsch Med Wochenschr. 2003 Feb 21;128(8):378-85. doi: 10.1055/s-2003-37378. Dtsch Med Wochenschr. 2003. PMID: 12594624 Review. German. No abstract available.

7

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

Schaeffeler E, Schwab M, Eichelbaum M, Zanger UM. Schaeffeler E, et al. Hum Mutat. 2003 Dec;22(6):476-85. doi: 10.1002/humu.10280. Hum Mutat. 2003. PMID: 14635107

8

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

Hitzl M, Schaeffeler E, Hocher B, Slowinski T, Halle H, Eichelbaum M, Kaufmann P, Fritz P, Fromm MF, Schwab M. Hitzl M, et al. Among authors: schaeffeler e. Pharmacogenetics. 2004 May;14(5):309-18. doi: 10.1097/00008571-200405000-00006. Pharmacogenetics. 2004. PMID: 15115917

9

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants.

Schaeffeler E, Fischer C, Brockmeier D, Wernet D, Moerike K, Eichelbaum M, Zanger UM, Schwab M. Schaeffeler E, et al. Pharmacogenetics. 2004 Jul;14(7):407-17. doi: 10.1097/01.fpc.0000114745.08559.db. Pharmacogenetics. 2004. PMID: 15226673

10

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).

Niemi M, Schaeffeler E, Lang T, Fromm MF, Neuvonen M, Kyrklund C, Backman JT, Kerb R, Schwab M, Neuvonen PJ, Eichelbaum M, Kivistö KT. Niemi M, et al. Among authors: schaeffeler e. Pharmacogenetics. 2004 Jul;14(7):429-40. doi: 10.1097/01.fpc.0000114750.08559.32. Pharmacogenetics. 2004. PMID: 15226675

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