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Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung Diseases.
Zhao AY, Unterman A, Abu Hussein N, Sharma P, Flint J, Yan X, Adams TS, Justet A, Sumida TS, Zhao J, Schupp JC, Raredon MSB, Ahangari F, Zhang Y, Buendia-Roldan I, Adegunsoye A, Sperling AI, Prasse A, Ryu C, Herzog E, Selman M, Pardo A, Kaminski N. Zhao AY, et al. Among authors: yan x. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558301. doi: 10.1101/2023.09.20.558301. bioRxiv. 2023. PMID: 37786685 Free PMC article. Preprint.
Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.
Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, Britto CJ. Schupp JC, et al. Among authors: yan x. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1419-1429. doi: 10.1164/rccm.202004-0991OC. Am J Respir Crit Care Med. 2020. PMID: 32603604 Free PMC article.
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis.
Adams TS, Schupp JC, Poli S, Ayaub EA, Neumark N, Ahangari F, Chu SG, Raby BA, DeIuliis G, Januszyk M, Duan Q, Arnett HA, Siddiqui A, Washko GR, Homer R, Yan X, Rosas IO, Kaminski N. Adams TS, et al. Among authors: yan x. Sci Adv. 2020 Jul 8;6(28):eaba1983. doi: 10.1126/sciadv.aba1983. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832599 Free PMC article.
Toward a Cell Atlas of the Human Airway.
Schupp JC, Yan X, Kaminski N. Schupp JC, et al. Among authors: yan x. Am J Respir Crit Care Med. 2020 Dec 15;202(12):1611-1612. doi: 10.1164/rccm.202007-2977ED. Am J Respir Crit Care Med. 2020. PMID: 32841575 Free PMC article. No abstract available.
Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity.
Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, Lucas CL. Ramaswamy A, et al. Among authors: yan x. medRxiv [Preprint]. 2021 Apr 3:2020.12.01.20241364. doi: 10.1101/2020.12.01.20241364. medRxiv. 2021. Update in: Immunity. 2021 May 11;54(5):1083-1095.e7. doi: 10.1016/j.immuni.2021.04.003 PMID: 33300011 Free PMC article. Updated. Preprint.
Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency.
Chu JH, Zang W, Vukmirovic M, Yan X, Adams T, DeIuliis G, Hu B, Mihaljinec A, Schupp JC, Becich MJ, Hochheiser H, Gibson KF, Chen ES, Morris A, Leader JK, Wisniewski SR, Zhang Y, Sciurba FC, Collman RG, Sandhaus R, Herzog EL, Patterson KC, Sauler M, Strange C, Kaminski N; GRADS Investigators. Chu JH, et al. Among authors: yan x. Thorax. 2021 Feb;76(2):134-143. doi: 10.1136/thoraxjnl-2019-214301. Epub 2020 Dec 10. Thorax. 2021. PMID: 33303696 Free PMC article.
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children.
Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, Lucas CL. Ramaswamy A, et al. Among authors: yan x. Immunity. 2021 May 11;54(5):1083-1095.e7. doi: 10.1016/j.immuni.2021.04.003. Epub 2021 Apr 13. Immunity. 2021. PMID: 33891889 Free PMC article.
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.
Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Schupp JC, et al. Among authors: yan x. Circulation. 2021 Jul 27;144(4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. Epub 2021 May 25. Circulation. 2021. PMID: 34030460 Free PMC article.
Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis.
Vukmirovic M, Yan X, Gibson KF, Gulati M, Schupp JC, DeIuliis G, Adams TS, Hu B, Mihaljinec A, Woolard TN, Lynn H, Emeagwali N, Herzog EL, Chen ES, Morris A, Leader JK, Zhang Y, Garcia JGN, Maier LA, Collman RG, Drake WP, Becich MJ, Hochheiser H, Wisniewski SR, Benos PV, Moller DR, Prasse A, Koth LL, Kaminski N; GRADS Investigators. Vukmirovic M, et al. Among authors: yan x. Eur Respir J. 2021 Dec 2;58(6):2002950. doi: 10.1183/13993003.02950-2020. Print 2021 Dec. Eur Respir J. 2021. PMID: 34083402 Free PMC article.
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