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Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade.
Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D, Martin ML, Elemento O, Cubillos-Ruiz JR, McGraw TE, Altorki NK, Mittal V. Markowitz GJ, et al. Among authors: he y. Res Sq [Preprint]. 2023 Sep 21:rs.3.rs-3356477. doi: 10.21203/rs.3.rs-3356477/v1. Res Sq. 2023. Update in: Nat Immunol. 2024 Oct;25(10):1884-1899. doi: 10.1038/s41590-024-01963-1 PMID: 37790365 Free PMC article. Updated. Preprint.
The regulation of CD73 in non-small cell lung cancer.
Han Y, Lee T, He Y, Raman R, Irizarry A, Martin ML, Giaccone G. Han Y, et al. Among authors: he y. Eur J Cancer. 2022 Jul;170:91-102. doi: 10.1016/j.ejca.2022.04.025. Epub 2022 May 19. Eur J Cancer. 2022. PMID: 35598361
A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
He Y, Kim IK, Bian J, Polyzos A, Di Giammartino DC, Zhang YW, Luo J, Hernandez MO, Kedei N, Cam M, Borczuk AC, Lee T, Han Y, Conner EA, Wong M, Tillo DC, Umemura S, Chen V, Ruan L, White JB, Miranda IC, Awasthi PP, Altorki NK, Divakar P, Elemento O, Apostolou E, Giaccone G. He Y, et al. J Thorac Oncol. 2022 Dec;17(12):1375-1386. doi: 10.1016/j.jtho.2022.08.008. Epub 2022 Aug 30. J Thorac Oncol. 2022. PMID: 36049655 Free PMC article.
Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve immunotherapy.
Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D, Martin ML, Elemento O, Cubillos-Ruiz JR, McGraw TE, Altorki NK, Mittal V. Markowitz GJ, et al. Among authors: he y. Nat Immunol. 2024 Oct;25(10):1884-1899. doi: 10.1038/s41590-024-01963-1. Epub 2024 Sep 26. Nat Immunol. 2024. PMID: 39327500
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