Zdovc I - Search Results

1

Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (-)-epicatechin.

Rambaher MH, Zdovc I, Glavač NK, Gobec S, Frlan R. Rambaher MH, et al. Among authors: zdovc i. J Comput Aided Mol Des. 2023 Dec;37(12):721-733. doi: 10.1007/s10822-023-00535-z. Epub 2023 Oct 5. J Comput Aided Mol Des. 2023. PMID: 37796382 Free PMC article.

2

Mur ligases inhibitors with azastilbene scaffold: Expanding the structure-activity relationship.

Hrast M, Frlan R, Knez D, Zdovc I, Barreteau H, Gobec S. Hrast M, et al. Among authors: zdovc i. Bioorg Med Chem Lett. 2021 May 15;40:127966. doi: 10.1016/j.bmcl.2021.127966. Epub 2021 Mar 17. Bioorg Med Chem Lett. 2021. PMID: 33744441

3

Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead.

Grabrijan K, Hrast M, Proj M, Dolšak A, Zdovc I, Imre T, Petri L, Ábrányi-Balogh P, Keserű GM, Gobec S. Grabrijan K, et al. Among authors: zdovc i. Eur J Med Chem. 2022 Dec 5;243:114752. doi: 10.1016/j.ejmech.2022.114752. Epub 2022 Sep 13. Eur J Med Chem. 2022. PMID: 36126388 Free article.

4

Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s).

Grabrijan K, Benedik NS, Krajnc A, Bozovičar K, Knez D, Proj M, Zdovc I, Sosič I, Contreras-Martel C, Dessen A, Rambaher MH, Gobec S. Grabrijan K, et al. Among authors: zdovc i. Acta Pharm. 2024 Sep 14;74(3):423-440. doi: 10.2478/acph-2024-0024. Print 2024 Sep 1. Acta Pharm. 2024. PMID: 39279527 Free article.

5

Diminishing hERG inhibitory activity of aminopiperidine-naphthyridine linked NBTI antibacterials by structural and physicochemical optimizations.

Kokot M, Weiss M, Zdovc I, Anderluh M, Hrast M, Minovski N. Kokot M, et al. Among authors: zdovc i. Bioorg Chem. 2022 Nov;128:106087. doi: 10.1016/j.bioorg.2022.106087. Epub 2022 Aug 11. Bioorg Chem. 2022. PMID: 35970069

6

A Fine-Tuned Lipophilicity/Hydrophilicity Ratio Governs Antibacterial Potency and Selectivity of Bifurcated Halogen Bond-Forming NBTIs.

Kolarič A, Kokot M, Hrast M, Weiss M, Zdovc I, Trontelj J, Žakelj S, Anderluh M, Minovski N. Kolarič A, et al. Among authors: zdovc i. Antibiotics (Basel). 2021 Jul 15;10(7):862. doi: 10.3390/antibiotics10070862. Antibiotics (Basel). 2021. PMID: 34356782 Free PMC article.

7

Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy.

Kokot M, Weiss M, Zdovc I, Senerovic L, Radakovic N, Anderluh M, Minovski N, Hrast M. Kokot M, et al. Among authors: zdovc i. Eur J Med Chem. 2023 Mar 15;250:115160. doi: 10.1016/j.ejmech.2023.115160. Epub 2023 Feb 2. Eur J Med Chem. 2023. PMID: 36753879 Free article.

8

Benzodioxane-Benzamides as Antibacterial Agents: Computational and SAR Studies to Evaluate the Influence of the 7-Substitution in FtsZ Interaction.

Straniero V, Sebastián-Pérez V, Hrast M, Zanotto C, Casiraghi A, Suigo L, Zdovc I, Radaelli A, De Giuli Morghen C, Valoti E. Straniero V, et al. Among authors: zdovc i. ChemMedChem. 2020 Jan 17;15(2):195-209. doi: 10.1002/cmdc.201900537. Epub 2019 Dec 11. ChemMedChem. 2020. PMID: 31750973 Free article.

9

Exploring Alternative Pathways to Target Bacterial Type II Topoisomerases Using NBTI Antibacterials: Beyond Halogen-Bonding Interactions.

Kokot M, Novak D, Zdovc I, Anderluh M, Hrast M, Minovski N. Kokot M, et al. Among authors: zdovc i. Antibiotics (Basel). 2023 May 18;12(5):930. doi: 10.3390/antibiotics12050930. Antibiotics (Basel). 2023. PMID: 37237833 Free PMC article.

10

Cyclohexyl amide-based novel bacterial topoisomerase inhibitors with prospective GyrA-binding fragments.

Kolarič A, Novak D, Weiss M, Hrast M, Zdovc I, Anderluh M, Minovski N. Kolarič A, et al. Among authors: zdovc i. Future Med Chem. 2019 May;11(9):935-945. doi: 10.4155/fmc-2018-0472. Epub 2019 May 29. Future Med Chem. 2019. PMID: 31140866

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