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A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Mizi A, Papantonis A, Vatsellas G, Galanos P, Bartek J, Petty R, Serrano M, Thanos D, Roussos C, Demaria M, Evangelou K, Gorgoulis VG. Magkouta S, et al. Among authors: georgiou m. Mol Cell. 2023 Oct 5;83(19):3558-3573.e7. doi: 10.1016/j.molcel.2023.09.006. Mol Cell. 2023. PMID: 37802028 Free article.
Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.
Nikolaou PE, Lambrinidis G, Georgiou M, Karagiannis D, Efentakis P, Bessis-Lazarou P, Founta K, Kampoukos S, Konstantin V, Palmeira CM, Davidson SM, Lougiakis N, Marakos P, Pouli N, Mikros E, Andreadou I. Nikolaou PE, et al. Among authors: georgiou m. J Med Chem. 2023 Nov 23;66(22):15115-15140. doi: 10.1021/acs.jmedchem.3c01048. Epub 2023 Nov 9. J Med Chem. 2023. PMID: 37943012
One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Kyrodimos E, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Vatsellas G, Petty R, Thanos D, Demaria M, Evangelou K, Di Micco R, Gorgoulis VG. Magkouta S, et al. Among authors: georgiou m. STAR Protoc. 2024 Mar 15;5(1):102929. doi: 10.1016/j.xpro.2024.102929. Epub 2024 Mar 8. STAR Protoc. 2024. PMID: 38460134 Free PMC article.
Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor.
Huang X, Chorianopoulou A, Kalkounou P, Georgiou M, Pousias A, Davies A, Pearce A, Harris M, Lambrinidis G, Marakos P, Pouli N, Kolocouris A, Lougiakis N, Ladds G. Huang X, et al. Among authors: georgiou m. J Med Chem. 2024 Aug 8;67(15):13117-13146. doi: 10.1021/acs.jmedchem.4c01092. Epub 2024 Jul 29. J Med Chem. 2024. PMID: 39073853 Free PMC article.
Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog.
Magkouta S, Veroutis D, Papaspyropoulos A, Georgiou M, Lougiakis N, Pippa N, Havaki S, Palaiologou A, Thanos DF, Kambas K, Lagopati N, Boukos N, Pouli N, Marakos P, Kotsinas A, Thanos D, Evangelou K, Sampaziotis F, Tamvakopoulos C, Pispas S, Petty R, Kotopoulos N, Gorgoulis VG. Magkouta S, et al. Among authors: georgiou m. Nat Aging. 2024 Dec 27. doi: 10.1038/s43587-024-00747-4. Online ahead of print. Nat Aging. 2024. PMID: 39730824
Patients achieving low lupus disease activity state, systemic lupus erythematosus disease control or remission showed lower rates of organ damage during longitudinal follow-up: analysis of the Hopkins Lupus Cohort.
Hunnicutt J, Georgiou ME, Richards A, Quasny H, Magder L, Goldman D, Petri MA. Hunnicutt J, et al. Among authors: georgiou me. Lupus Sci Med. 2024 Dec 11;11(2):e001206. doi: 10.1136/lupus-2024-001206. Lupus Sci Med. 2024. PMID: 39663154 Free PMC article.
297 results