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Page 1
Metabolic support by macrophages sustains colonic epithelial homeostasis.
Fritsch SD, Sukhbaatar N, Gonzales K, Sahu A, Tran L, Vogel A, Mazic M, Wilson JL, Forisch S, Mayr H, Oberle R, Weiszmann J, Brenner M, Vanhoutte R, Hofmann M, Pirnes-Karhu S, Magnes C, Kühnast T, Weckwerth W, Bock C, Klavins K, Hengstschläger M, Moissl-Eichinger C, Schabbauer G, Egger G, Pirinen E, Verhelst SHL, Weichhart T. Fritsch SD, et al. Cell Metab. 2023 Nov 7;35(11):1931-1943.e8. doi: 10.1016/j.cmet.2023.09.010. Epub 2023 Oct 6. Cell Metab. 2023. PMID: 37804836 Free article.
Effects of Interferons and Viruses on Metabolism.
Fritsch SD, Weichhart T. Fritsch SD, et al. Front Immunol. 2016 Dec 21;7:630. doi: 10.3389/fimmu.2016.00630. eCollection 2016. Front Immunol. 2016. PMID: 28066439 Free PMC article. Review.
Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Wilson JL, et al. Among authors: fritsch sd. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011. Cell Rep. 2020. PMID: 32023468 Free PMC article.
Duodenal macrophages control dietary iron absorption via local degradation of transferrin.
Sukhbaatar N, Schöller M, Fritsch SD, Linke M, Horer S, Träger M, Mazić M, Forisch S, Gonzales K, Kahler JP, Binder C, Lassnig C, Strobl B, Müller M, Scheiber-Mojdehkar B, Gundacker C, Dabsch S, Kain R, Hengstschläger M, Verhelst SHL, Weiss G, Theurl I, Weichhart T. Sukhbaatar N, et al. Among authors: fritsch sd. Blood. 2023 Jun 8;141(23):2878-2890. doi: 10.1182/blood.2022016632. Blood. 2023. PMID: 37018657 Free PMC article.
mTORC1 and mTORC2 as regulators of cell metabolism in immunity.
Linke M, Fritsch SD, Sukhbaatar N, Hengstschläger M, Weichhart T. Linke M, et al. Among authors: fritsch sd. FEBS Lett. 2017 Oct;591(19):3089-3103. doi: 10.1002/1873-3468.12711. Epub 2017 Jun 23. FEBS Lett. 2017. PMID: 28600802 Free PMC article. Review.
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T. Katholnig K, et al. Among authors: fritsch sd. JCI Insight. 2019 Oct 17;4(20):e124164. doi: 10.1172/jci.insight.124164. JCI Insight. 2019. PMID: 31619583 Free PMC article.