Vander Heiden J - Search Results

1

A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.

Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ; UCSF COMET Consortium; Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM. Hackney JA, et al. Among authors: vander heiden j. iScience. 2023 Sep 1;26(10):107813. doi: 10.1016/j.isci.2023.107813. eCollection 2023 Oct 20. iScience. 2023. PMID: 37810211 Free PMC article.

2

Isoform-selective TGF-β3 inhibition for systemic sclerosis.

Sun T, Vander Heiden JA, Gao X, Yin J, Uttarwar S, Liang WC, Jia G, Yadav R, Huang Z, Mitra M, Halpern W, Bender HS, Brightbill HD, Wu Y, Lupardus P, Ramalingam T, Arron JR. Sun T, et al. Among authors: vander heiden ja. Med. 2024 Feb 9;5(2):132-147.e7. doi: 10.1016/j.medj.2023.12.011. Epub 2024 Jan 24. Med. 2024. PMID: 38272035 Free article.

3

A cell atlas foundation model for scalable search of similar human cells.

Heimberg G, Kuo T, DePianto DJ, Salem O, Heigl T, Diamant N, Scalia G, Biancalani T, Turley SJ, Rock JR, Corrada Bravo H, Kaminker J, Vander Heiden JA, Regev A. Heimberg G, et al. Among authors: vander heiden ja. Nature. 2024 Nov 20. doi: 10.1038/s41586-024-08411-y. Online ahead of print. Nature. 2024. PMID: 39566551

4

Impact of Canada's cannabis legalisation on youth emergency department visits for cannabis-related disorders and poisoning in Ontario and Alberta, 2015-2019.

Callaghan RC, Sanches M, Vander Heiden J, Kish SJ. Callaghan RC, et al. Among authors: vander heiden j. Drug Alcohol Rev. 2023 Jul;42(5):1104-1113. doi: 10.1111/dar.13637. Epub 2023 Mar 13. Drug Alcohol Rev. 2023. PMID: 36908258

5

Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone.

Ma HY, Vander Heiden JA, Uttarwar S, Xi Y, N'Diaye EN, LaCanna R, Caplazi P, Gierke S, Moffat J, Wolters PJ, Ding N. Ma HY, et al. Among authors: vander heiden ja. Eur Respir J. 2023 Apr 27;61(4):2200604. doi: 10.1183/13993003.00604-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36585256 Free PMC article.

6

A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.

Xi Y, LaCanna R, Ma HY, N'Diaye EN, Gierke S, Caplazi P, Sagolla M, Huang Z, Lucio L, Arlantico A, Jeet S, Brightbill H, Emson C, Wong A, Morshead KB, DePianto DJ, Roose-Girma M, Yu C, Tam L, Jia G, Ramalingam TR, Marsters S, Ashkenazi A, Kim SH, Kelly R, Wu S, Wolters PJ, Feldstein AE, Vander Heiden JA, Ding N. Xi Y, et al. Among authors: vander heiden ja. Cell Metab. 2022 Sep 6;34(9):1377-1393.e8. doi: 10.1016/j.cmet.2022.07.009. Epub 2022 Aug 19. Cell Metab. 2022. PMID: 35987202 Free article.

7

In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.

Browder KC, Reddy P, Yamamoto M, Haghani A, Guillen IG, Sahu S, Wang C, Luque Y, Prieto J, Shi L, Shojima K, Hishida T, Lai Z, Li Q, Choudhury FK, Wong WR, Liang Y, Sangaraju D, Sandoval W, Esteban CR, Delicado EN, Garcia PG, Pawlak M, Vander Heiden JA, Horvath S, Jasper H, Izpisua Belmonte JC. Browder KC, et al. Among authors: vander heiden ja. Nat Aging. 2022 Mar;2(3):243-253. doi: 10.1038/s43587-022-00183-2. Epub 2022 Mar 7. Nat Aging. 2022. PMID: 37118377

8

Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.

Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. Headland SE, et al. Among authors: vander heiden j. Sci Transl Med. 2022 Jan 12;14(627):eabf8188. doi: 10.1126/scitranslmed.abf8188. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020406

9

Canada's cannabis legalization and drivers' traffic-injury presentations to emergency departments in Ontario and Alberta, 2015-2019.

Callaghan RC, Sanches M, Vander Heiden J, Asbridge M, Stockwell T, Macdonald S, Peterman BH, Kish SJ. Callaghan RC, et al. Among authors: vander heiden j. Drug Alcohol Depend. 2021 Nov 1;228:109008. doi: 10.1016/j.drugalcdep.2021.109008. Epub 2021 Aug 27. Drug Alcohol Depend. 2021. PMID: 34508959

10

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.

Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR. Sun T, et al. Among authors: vander heiden ja. Sci Transl Med. 2021 Aug 4;13(605):eabe0407. doi: 10.1126/scitranslmed.abe0407. Sci Transl Med. 2021. PMID: 34349032

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