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STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation.
Xie J, Sheng M, Rong S, Zhou D, Wang C, Wu W, Huang J, Sun Y, Wang Y, Chen P, Wu Y, Wang Y, Wang L, Zhou BO, Huang X, Walsh CP, Bohlander SK, Huang J, Wang X, Xu GL, Gao H, Shi Y. Xie J, et al. Among authors: shi y. Leukemia. 2023 Dec;37(12):2457-2467. doi: 10.1038/s41375-023-02055-z. Epub 2023 Oct 10. Leukemia. 2023. PMID: 37816954 Free PMC article.
STING is crucial for the survival of RUNX1::RUNX1T1 leukemia cells.
Sun Y, Wu Y, Pang G, Huang J, Sheng M, Xie J, Chen P, Wang Y, Yin D, Zhao G, Bohlander SK, Huang J, Xu GL, Gao H, Zhou D, Shi Y. Sun Y, et al. Among authors: shi y. Leukemia. 2024 Oct;38(10):2102-2114. doi: 10.1038/s41375-024-02383-8. Epub 2024 Aug 23. Leukemia. 2024. PMID: 39179670
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