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386 results

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Page 1
Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer.
Kinose Y, Xu H, Kim H, Kumar S, Shan X, George E, Wang X, Medvedev S, Ferman B, Gitto SB, Whicker M, D'Andrea K, Wubbenhorst B, Hallberg D, O'Connor M, Schwartz LE, Hwang WT, Nathanson KL, Mills GB, Velculescu VE, Wang TL, Brown EJ, Drapkin R, Simpkins F. Kinose Y, et al. Among authors: nathanson kl. Res Sq [Preprint]. 2023 Sep 27:rs.3.rs-3314138. doi: 10.21203/rs.3.rs-3314138/v1. Res Sq. 2023. PMID: 37841875 Free PMC article. Preprint.
BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers.
Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D'Andrea K, Daber R, Morrissette JJD, Mitra N, Feldman M, Domchek SM, Nathanson KL. Maxwell KN, et al. Among authors: nathanson kl. Nat Commun. 2017 Aug 22;8(1):319. doi: 10.1038/s41467-017-00388-9. Nat Commun. 2017. PMID: 28831036 Free PMC article.
Filaggrin sequencing and bioinformatics tools.
Margolis DJ, Mitra N, Wubbenhorst B, Nathanson KL. Margolis DJ, et al. Among authors: nathanson kl. Arch Dermatol Res. 2020 Mar;312(2):155-158. doi: 10.1007/s00403-019-01956-3. Epub 2019 Aug 1. Arch Dermatol Res. 2020. PMID: 31372728 Free PMC article.
Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.
Shah JB, Pueschl D, Wubbenhorst B, Fan M, Pluta J, D'Andrea K, Hubert AP, Shilan JS, Zhou W, Kraya AA, Llop Guevara A, Ruan C, Serra V, Balmaña J, Feldman M, Morin PJ, Nayak A, Maxwell KN, Domchek SM, Nathanson KL. Shah JB, et al. Among authors: nathanson kl. Nat Commun. 2022 Nov 7;13(1):6728. doi: 10.1038/s41467-022-34523-y. Nat Commun. 2022. PMID: 36344544 Free PMC article.
ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma.
Rebecca V, Jagirdar K, Portuallo M, Wei M, Wilhide M, Bravo J, Robertson B, Alicea G, Aguh C, Xiao M, Godok T, Fingerman D, Brown G, Herlyn M, Guo B, Toska E, Zabransky D, Wubbenhorst B, Nathanson K, Kwatra S, Goyal Y, Ji H, Liu Q. Rebecca V, et al. Res Sq [Preprint]. 2023 Apr 20:rs.3.rs-2817876. doi: 10.21203/rs.3.rs-2817876/v1. Res Sq. 2023. Update in: Oncogene. 2024 Feb;43(6):395-405. doi: 10.1038/s41388-023-02900-6 PMID: 37131684 Free PMC article. Updated. Preprint.
Biallelic BRCA Loss and Homologous Recombination Deficiency in Nonbreast/Ovarian Tumors in Germline BRCA1/2 Carriers.
Wineland D, Le AN, Hausler R, Kelly G, Barrett E, Desai H, Wubbenhorst B, Pluta J, Bastian P, Symecko H, D'Andrea K, Doucette A, Gabriel P, Reiss KA, Nayak A, Feldman M, Domchek SM, Nathanson KL, Maxwell KN; Regeneron Genetics Center; Penn Medicine Biobank. Wineland D, et al. Among authors: nathanson kl. JCO Precis Oncol. 2023 Aug;7:e2300036. doi: 10.1200/PO.23.00036. JCO Precis Oncol. 2023. PMID: 37535879 Free PMC article.
ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma.
Jagirdar K, Portuallo ME, Wei M, Wilhide M, Bravo Narula JA, Robertson BM, Alicea GM, Aguh C, Xiao M, Godok T, Fingerman D, Brown GS, Herlyn M, Elad VM, Guo X, Toska E, Zabransky DJ, Wubbenhorst B, Nathanson KL, Kwatra S, Goyal Y, Ji H, Liu Q, Rebecca VW. Jagirdar K, et al. Among authors: nathanson kl. Oncogene. 2024 Feb;43(6):395-405. doi: 10.1038/s41388-023-02900-6. Epub 2023 Dec 8. Oncogene. 2024. PMID: 38066089 Free PMC article.
Integrated Molecular Characterization of Testicular Germ Cell Tumors.
Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, Reuter VE, Godoy G, Jones J, Shelley CS, Feldman DR, Vidal DO, Lessel D, Kulis T, Cárcano FM, Leraas KM, Lichtenberg TM, Brooks D, Cherniack AD, Cho J, Heiman DI, Kasaian K, Liu M, Noble MS, Xi L, Zhang H, Zhou W, ZenKlusen JC, Hutter CM, Felau I, Zhang J, Schultz N, Getz G, Meyerson M, Stuart JM; Cancer Genome Atlas Research Network; Akbani R, Wheeler DA, Laird PW, Nathanson KL, Cortessis VK, Hoadley KA. Shen H, et al. Among authors: nathanson kl. Cell Rep. 2018 Jun 12;23(11):3392-3406. doi: 10.1016/j.celrep.2018.05.039. Cell Rep. 2018. PMID: 29898407 Free PMC article.
386 results