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Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC, Wang N, Chen Y, Inoue Y, Shue F, Ren Y, Wang M, Qiao W, Ikezu TC, Li Z, Zhao J, Martens Y, Doss SV, Rosenberg CL, Jeevaratnam S, Jia L, Raulin AC, Qi F, Zhu Y, Alnobani A, Knight J, Chen Y, Linares C, Kurti A, Fryer JD, Zhang B, Wu LJ, Kim BYS, Bu G. Liu CC, et al. Among authors: bu g. Nat Immunol. 2023 Nov;24(11):1854-1866. doi: 10.1038/s41590-023-01640-9. Epub 2023 Oct 19. Nat Immunol. 2023. PMID: 37857825
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: bu g. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.
Neuronal clearance of amyloid-β by endocytic receptor LRP1.
Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Kanekiyo T, et al. Among authors: bu g. J Neurosci. 2013 Dec 4;33(49):19276-83. doi: 10.1523/JNEUROSCI.3487-13.2013. J Neurosci. 2013. PMID: 24305823 Free PMC article.
594 results