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Page 1
Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor.
Willems HMG, Edwards S, Boffey HK, Chawner SJ, Green C, Romero T, Winpenny D, Skidmore J, Clarke JH, Andrews SP. Willems HMG, et al. Among authors: winpenny d. RSC Med Chem. 2023 Apr 17;14(5):934-946. doi: 10.1039/d3md00039g. eCollection 2023 May 25. RSC Med Chem. 2023. PMID: 37252102 Free PMC article.
Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.
Boffey HK, Rooney TPC, Willems HMG, Edwards S, Green C, Howard T, Ogg D, Romero T, Scott DE, Winpenny D, Duce J, Skidmore J, Clarke JH, Andrews SP. Boffey HK, et al. Among authors: winpenny d. J Med Chem. 2022 Feb 24;65(4):3359-3370. doi: 10.1021/acs.jmedchem.1c01819. Epub 2022 Feb 11. J Med Chem. 2022. PMID: 35148092 Free PMC article.
Use of libraries to access new chemical space: applications to CRTH2.
Abid Masood M, Gardner M, Dack K, Winpenny D, Lunn G. Abid Masood M, et al. Among authors: winpenny d. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3682-7. doi: 10.1016/j.bmcl.2012.04.041. Epub 2012 Apr 20. Bioorg Med Chem Lett. 2012. PMID: 22560471