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Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan S, Schöpe PC, Lewis J, Putzker K, Uhrig U, Specker E, von Kries JP, Lindemann P, Omran A, Sanchez-Ibarra HE, Unger A, Zischinsky ML, Klebl B, Walther W, Nazaré M, Kobelt D, Stein U. Yan S, et al. Among authors: klebl b. Biomed Pharmacother. 2023 Dec;168:115698. doi: 10.1016/j.biopha.2023.115698. Epub 2023 Oct 21. Biomed Pharmacother. 2023. PMID: 37865992 Free article.
Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.
Aarhus TI, Bjørnstad F, Wolowczyk C, Larsen KU, Rognstad L, Leithaug T, Unger A, Habenberger P, Wolf A, Bjørkøy G, Pridans C, Eickhoff J, Klebl B, Hoff BH, Sundby E. Aarhus TI, et al. Among authors: klebl b. J Med Chem. 2023 May 25;66(10):6959-6980. doi: 10.1021/acs.jmedchem.3c00428. Epub 2023 May 16. J Med Chem. 2023. PMID: 37191268 Free PMC article.
Pyrrolopyrimidine based CSF1R inhibitors: Attempted departure from Flatland.
Bjørnstad F, Havik S, Aarhus TI, Mahdi I, Unger A, Habenberger P, Degenhart C, Eickhoff J, Klebl BM, Sundby E, Hoff BH. Bjørnstad F, et al. Among authors: klebl bm. Eur J Med Chem. 2024 Feb 5;265:116053. doi: 10.1016/j.ejmech.2023.116053. Epub 2023 Dec 17. Eur J Med Chem. 2024. PMID: 38141285 Free article.
An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity.
Yu D, Wagner S, Schütz M, Jeon Y, Seo M, Kim J, Brückner N, Kicuntod J, Tillmanns J, Wangen C, Hahn F, Kaufer BB, Neipel F, Eickhoff J, Klebl B, Nam K, Marschall M. Yu D, et al. Among authors: klebl b. Pharmaceutics. 2024 Jan 23;16(2):158. doi: 10.3390/pharmaceutics16020158. Pharmaceutics. 2024. PMID: 38399219 Free PMC article.
ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis.
Cibir Z, Hassel J, Sonneck J, Kowitz L, Beer A, Kraus A, Hallekamp G, Rosenkranz M, Raffelberg P, Olfen S, Smilowski K, Burkard R, Helfrich I, Tuz AA, Singh V, Ghosh S, Sickmann A, Klebl AK, Eickhoff JE, Klebl B, Seidl K, Chen J, Grabmaier A, Viga R, Gunzer M. Cibir Z, et al. Among authors: klebl b. Nat Commun. 2023 Dec 11;14(1):8103. doi: 10.1038/s41467-023-43765-3. Nat Commun. 2023. PMID: 38081825 Free PMC article.
75 results