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Page 1
ThermoBRET: A Ligand-Engagement Nanoscale Thermostability Assay Applied to GPCRs.
Hoare BL, Tippett DN, Kaur A, Cullum SA, Miljuš T, Koers EJ, Harwood CR, Dijon N, Holliday ND, Sykes DA, Veprintsev DB. Hoare BL, et al. Among authors: holliday nd. Chembiochem. 2024 Jan 15;25(2):e202300459. doi: 10.1002/cbic.202300459. Epub 2023 Nov 28. Chembiochem. 2024. PMID: 37872746
High-throughput kinetics in drug discovery.
Pinto MF, Sirina J, Holliday ND, McWhirter CL. Pinto MF, et al. Among authors: holliday nd. SLAS Discov. 2024 Jul;29(5):100170. doi: 10.1016/j.slasd.2024.100170. Epub 2024 Jul 3. SLAS Discov. 2024. PMID: 38964171 Free article. Review.
Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays.
Ertl FJ, Kopanchuk S, Dijon NC, Veikšina S, Tahk MJ, Laasfeld T, Schettler F, Gattor AO, Hübner H, Archipowa N, Köckenberger J, Heinrich MR, Gmeiner P, Kutta RJ, Holliday ND, Rinken A, Keller M. Ertl FJ, et al. Among authors: holliday nd. J Med Chem. 2024 Sep 26;67(18):16664-16691. doi: 10.1021/acs.jmedchem.4c01470. Epub 2024 Sep 11. J Med Chem. 2024. PMID: 39261089 Free PMC article.
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.
Talamonti E, Davegardh J, Kalinovich A, van Beek SMM, Dehvari N, Halleskog C, Bokhari HM, Hutchinson DS, Ham S, Humphrys LJ, Dijon NC, Motso A, Sandstrom A, Zacharewicz E, Mutule I, Suna E, Spura J, Ditrychova K, Stoddart LA, Holliday ND, Wright SC, Lauschke VM, Nielsen S, Scheele C, Cheesman E, Hoeks J, Molenaar P, Summers RJ, Pelcman B, Yakala GK, Bengtsson T. Talamonti E, et al. Among authors: holliday nd. Mol Metab. 2024 Jul;85:101931. doi: 10.1016/j.molmet.2024.101931. Epub 2024 May 17. Mol Metab. 2024. PMID: 38796310 Free PMC article.
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, Al-Hosaini K, Bäck M, Baker JG, Barnes NM, Bathgate R, Beaulieu JM, Beck-Sickinger AG, Behrens M, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Cox HM, Csaba Z, Dahlgren C, Dent G, Douglas SD, Dournaud P, Eguchi S, Escher E, Filardo EJ, Fong T, Fumagalli M, Gainetdinov RR, Garelja ML, de Gasparo M, Gerard C, Gershengorn M, Gobeil F, Goodfriend TL, Goudet C, Grätz L, Gregory KJ, Gundlach AL, Hamann J, Hanson J, Hauger RL, Hay DL, Heinemann A, Herr D, Hollenberg MD, Holliday ND, Horiuchi M, Hoyer D, Hunyady L, Husain A, IJzerman AP, Inagami T, Jacobson KA, Jensen RT, Jockers R, Jonnalagadda D, Karnik S, Kaupmann K, Kemp J, Kennedy C, Kihara Y, Kitazawa T, Kozielewicz P, Kreienkamp HJ, Kukkonen JP, Langenhan T, Larhammar D, Leach K, Lecca D, Lee JD, Leeman SE, Leprince J, Li XX, Lolait SJ, Lupp A, Macrae R, Maguire J, … See abstract for full author list ➔ Alexander SPH, et al. Among authors: holliday nd. Br J Pharmacol. 2023 Oct;180 Suppl 2:S23-S144. doi: 10.1111/bph.16177. Br J Pharmacol. 2023. PMID: 38123151 Free article.
Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
Stockley ML, Benedetti G, Blencowe P, Boulton SJ, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Ferdinand A, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Higgins GS, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Zemla A, Heald RA. Stockley ML, et al. Among authors: holliday nd. J Med Chem. 2023 Feb 23. doi: 10.1021/acs.jmedchem.3c00204. Online ahead of print. J Med Chem. 2023. PMID: 36815444 No abstract available.
56 results