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Page 1
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase.
Liu JY, Kuna RS, Pinheiro LV, Nguyen PTT, Welles JE, Drummond JM, Murali N, Sharma PV, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE. Liu JY, et al. Among authors: megill e. Cell Metab. 2024 Oct 28:S1550-4131(24)00410-8. doi: 10.1016/j.cmet.2024.10.014. Online ahead of print. Cell Metab. 2024. PMID: 39471816
Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production.
Sharrow AC, Megill E, Chen AJ, Farooqi A, Tangudu NK, Uboveja A, McGonigal S, Hempel N, Snyder NW, Buckanovich RJ, Aird KM. Sharrow AC, et al. Among authors: megill e. Mol Metab. 2024 Nov;89:102031. doi: 10.1016/j.molmet.2024.102031. Epub 2024 Sep 19. Mol Metab. 2024. PMID: 39304063 Free PMC article.
SGLT2 inhibitors activate pantothenate kinase in the human heart.
Forelli N, Eaton D, Patel J, Bowman CE, Kawakami R, Kuznetsov IA, Li K, Brady C, Bedi K, Yang Y, Koya K, Megill E, Kanter DS, Smith LG, Bowman GR, Snyder N, Edwards J, Margulies K, Arany Z. Forelli N, et al. Among authors: megill e. bioRxiv [Preprint]. 2024 Jul 27:2024.07.26.605401. doi: 10.1101/2024.07.26.605401. bioRxiv. 2024. PMID: 39091820 Free PMC article. Preprint.
A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment.
Abraham E, Volmert B, Roule T, Huang L, Yu J, Williams AE, Cohen HM, Douglas A, Megill E, Morris A, Stronati E, Fueyo R, Zubillaga M, Elrod JW, Akizu N, Aguirre A, Estaras C. Abraham E, et al. Among authors: megill e. bioRxiv [Preprint]. 2024 Jul 12:2024.07.11.602981. doi: 10.1101/2024.07.11.602981. bioRxiv. 2024. PMID: 39026825 Free PMC article. Preprint.
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation.
Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK, Cole AR, Megill E, Kantner D, Chatoff A, Ahmad H, Marcinkiewicz MM, Disharoon JA, Graff S, Dahl ES, Hempel N, Stallaert W, Sidoli S, Bitler BG, Long DT, Snyder NW, Aird KM. Uboveja A, et al. Among authors: megill e. bioRxiv [Preprint]. 2024 Feb 11:2024.02.06.578742. doi: 10.1101/2024.02.06.578742. bioRxiv. 2024. PMID: 38370789 Free PMC article. Preprint.
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: megill e. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
Lactoylglutathione promotes inflammatory signaling in macrophages.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: megill e. bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561739. doi: 10.1101/2023.10.10.561739. bioRxiv. 2023. Update in: Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888 PMID: 37873172 Free PMC article. Updated. Preprint.
miR-182/183-Rasa1 axis induced macrophage polarization and redox regulation promotes repair after ischemic cardiac injury.
Yang Y, Johnson J, Troupes CD, Feldsott EA, Kraus L, Megill E, Bian Z, Asangwe N, Kino T, Eaton DM, Wang T, Wagner M, Ma L, Bryan C, Wallner M, Kubo H, Berretta RM, Khan M, Wang H, Kishore R, Houser SR, Mohsin S. Yang Y, et al. Among authors: megill e. Redox Biol. 2023 Nov;67:102909. doi: 10.1016/j.redox.2023.102909. Epub 2023 Sep 29. Redox Biol. 2023. PMID: 37801856 Free PMC article.
17 results