Dowling DJ - Search Results

1

Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen.

Doss-Gollin S, Thomas S, Brook B, Abedi K, Lebas C, Auderset F, Lugo-Rodriguez Y, Sanchez-Schmitz G, Dowling DJ, Levy O, van Haren SD. Doss-Gollin S, et al. Among authors: dowling dj. NPJ Vaccines. 2023 Oct 26;8(1):163. doi: 10.1038/s41541-023-00759-y. NPJ Vaccines. 2023. PMID: 37884538 Free PMC article.

2

Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways.

Philbin VJ, Dowling DJ, Gallington LC, Cortés G, Tan Z, Suter EE, Chi KW, Shuckett A, Stoler-Barak L, Tomai M, Miller RL, Mansfield K, Levy O. Philbin VJ, et al. Among authors: dowling dj. J Allergy Clin Immunol. 2012 Jul;130(1):195-204.e9. doi: 10.1016/j.jaci.2012.02.042. Epub 2012 Apr 21. J Allergy Clin Immunol. 2012. PMID: 22521247 Free PMC article.

3

The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes.

Dowling DJ, Tan Z, Prokopowicz ZM, Palmer CD, Matthews MA, Dietsch GN, Hershberg RM, Levy O. Dowling DJ, et al. PLoS One. 2013;8(3):e58164. doi: 10.1371/journal.pone.0058164. Epub 2013 Mar 4. PLoS One. 2013. PMID: 23483986 Free PMC article.

4

Ontogeny of early life immunity.

Dowling DJ, Levy O. Dowling DJ, et al. Trends Immunol. 2014 Jul;35(7):299-310. doi: 10.1016/j.it.2014.04.007. Epub 2014 May 28. Trends Immunol. 2014. PMID: 24880460 Free PMC article. Review.

5

The effect of stable macromolecular complexes of ionic polyphosphazene on HIV Gag antigen and on activation of human dendritic cells and presentation to T-cells.

Palmer CD, Ninković J, Prokopowicz ZM, Mancuso CJ, Marin A, Andrianov AK, Dowling DJ, Levy O. Palmer CD, et al. Among authors: dowling dj. Biomaterials. 2014 Oct;35(31):8876-8886. doi: 10.1016/j.biomaterials.2014.06.043. Epub 2014 Jul 11. Biomaterials. 2014. PMID: 25023392

6

The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes.

Ganapathi L, Van Haren S, Dowling DJ, Bergelson I, Shukla NM, Malladi SS, Balakrishna R, Tanji H, Ohto U, Shimizu T, David SA, Levy O. Ganapathi L, et al. Among authors: dowling dj. PLoS One. 2015 Aug 14;10(8):e0134640. doi: 10.1371/journal.pone.0134640. eCollection 2015. PLoS One. 2015. PMID: 26274907 Free PMC article.

7

Pediatric Vaccine Adjuvants: Components of the Modern Vaccinologist's Toolbox.

Dowling DJ, Levy O. Dowling DJ, et al. Pediatr Infect Dis J. 2015 Dec;34(12):1395-8. doi: 10.1097/INF.0000000000000893. Pediatr Infect Dis J. 2015. PMID: 26353029 Free PMC article. Review. No abstract available.

8

Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures.

Oh DY, Dowling DJ, Ahmed S, Choi H, Brightman S, Bergelson I, Berger ST, Sauld JF, Pettengill M, Kho AT, Pollack HJ, Steen H, Levy O. Oh DY, et al. Among authors: dowling dj. Mol Cell Proteomics. 2016 Jun;15(6):1877-94. doi: 10.1074/mcp.M115.055541. Epub 2016 Mar 1. Mol Cell Proteomics. 2016. PMID: 26933193 Free PMC article.

9

In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant.

van Haren SD, Ganapathi L, Bergelson I, Dowling DJ, Banks M, Samuels RC, Reed SG, Marshall JD, Levy O. van Haren SD, et al. Among authors: dowling dj. Cytokine. 2016 Jul;83:99-109. doi: 10.1016/j.cyto.2016.04.001. Epub 2016 Apr 12. Cytokine. 2016. PMID: 27081760 Free PMC article. Clinical Trial.

10

Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells.

Pettengill MA, van Haren SD, Li N, Dowling DJ, Bergelson I, Jans J, Ferwerda G, Levy O. Pettengill MA, et al. Among authors: dowling dj. Innate Immun. 2016 Aug;22(6):433-43. doi: 10.1177/1753425916651985. Epub 2016 Jun 1. Innate Immun. 2016. PMID: 27252169 Free PMC article.

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