Gallego J - Search Results

1

Exploring the HIV-1 Rev Recognition Element (RRE)-Rev Inhibitory Capacity and Antiretroviral Action of Benfluron Analogs.

Chumillas S, Loharch S, Beltrán M, Szewczyk MP, Bernal S, Puertas MC, Martinez-Picado J, Alcamí J, Bedoya LM, Marchán V, Gallego J. Chumillas S, et al. Among authors: gallego j. Molecules. 2023 Oct 11;28(20):7031. doi: 10.3390/molecules28207031. Molecules. 2023. PMID: 37894510 Free PMC article.

2

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

González-Bulnes L, Ibáñez I, Bedoya LM, Beltrán M, Catalán S, Alcamí J, Fustero S, Gallego J. González-Bulnes L, et al. Among authors: gallego j. Angew Chem Int Ed Engl. 2013 Dec 9;52(50):13405-9. doi: 10.1002/anie.201306665. Epub 2013 Nov 8. Angew Chem Int Ed Engl. 2013. PMID: 24214163 No abstract available.

3

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Prado S, Beltrán M, Coiras M, Bedoya LM, Alcamí J, Gallego J. Prado S, et al. Among authors: gallego j. Biochem Pharmacol. 2016 May 1;107:14-28. doi: 10.1016/j.bcp.2016.02.007. Epub 2016 Feb 17. Biochem Pharmacol. 2016. PMID: 26896646

4

A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference.

Prado S, Beltrán M, Moreno Á, Bedoya LM, Alcamí J, Gallego J. Prado S, et al. Among authors: gallego j. Biochem Pharmacol. 2018 Oct;156:68-77. doi: 10.1016/j.bcp.2018.07.040. Epub 2018 Jul 31. Biochem Pharmacol. 2018. PMID: 30071201

5

Nucleic acid recognition and antiviral activity of 1,4-substituted terphenyl compounds mimicking all faces of the HIV-1 Rev protein positively-charged α-helix.

Medina-Trillo C, Sedgwick DM, Herrera L, Beltrán M, Moreno Á, Barrio P, Bedoya LM, Alcamí J, Fustero S, Gallego J. Medina-Trillo C, et al. Among authors: gallego j. Sci Rep. 2020 Apr 28;10(1):7190. doi: 10.1038/s41598-020-64120-2. Sci Rep. 2020. PMID: 32346097 Free PMC article.

6

The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family.

Castillo-Martínez J, Fan L, Szewczyk MP, Wang YX, Gallego J. Castillo-Martínez J, et al. Among authors: gallego j. Nucleic Acids Res. 2022 Feb 28;50(4):2287-2301. doi: 10.1093/nar/gkac061. Nucleic Acids Res. 2022. PMID: 35137150 Free PMC article.

7

SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules.

Simba-Lahuasi A, Cantero-Camacho Á, Rosales R, McGovern BL, Rodríguez ML, Marchán V, White KM, García-Sastre A, Gallego J. Simba-Lahuasi A, et al. Among authors: gallego j. Pharmaceuticals (Basel). 2022 Nov 22;15(12):1448. doi: 10.3390/ph15121448. Pharmaceuticals (Basel). 2022. PMID: 36558898 Free PMC article.

8

Pharmacophore-Based Discovery of Viral RNA Conformational Modulators.

Martín-Villamil M, Sanmartín I, Moreno Á, Gallego J. Martín-Villamil M, et al. Among authors: gallego j. Pharmaceuticals (Basel). 2022 Jun 14;15(6):748. doi: 10.3390/ph15060748. Pharmaceuticals (Basel). 2022. PMID: 35745667 Free PMC article.

9

Sarbecovirus programmed ribosome frameshift RNA element folding studied by NMR spectroscopy and comparative analyses.

Hernández-Marín M, Cantero-Camacho Á, Mena I, López-Núñez S, García-Sastre A, Gallego J. Hernández-Marín M, et al. Among authors: gallego j. Nucleic Acids Res. 2024 Oct 28;52(19):11960-11972. doi: 10.1093/nar/gkae704. Nucleic Acids Res. 2024. PMID: 39149904 Free PMC article.

10

Analysis of mixed DNA-bisnaphthalimide interactions involving groove association and intercalation with surface-based and solution methodologies.

González-Bulnes L, Gallego J. González-Bulnes L, et al. Among authors: gallego j. Biopolymers. 2012 Dec;97(12):974-87. doi: 10.1002/bip.22114. Biopolymers. 2012. PMID: 22987588

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