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Page 1
Decoding aging-dependent regenerative decline across tissues at single-cell resolution.
Cai Y, Xiong M, Xin Z, Liu C, Ren J, Yang X, Lei J, Li W, Liu F, Chu Q, Zhang Y, Yin J, Ye Y, Liu D, Fan Y, Sun S, Jing Y, Zhao Q, Zhao L, Che S, Zheng Y, Yan H, Ma S, Wang S, Izpisua Belmonte JC, Qu J, Zhang W, Liu GH. Cai Y, et al. Among authors: izpisua belmonte jc. Cell Stem Cell. 2023 Dec 7;30(12):1674-1691.e8. doi: 10.1016/j.stem.2023.09.014. Epub 2023 Oct 27. Cell Stem Cell. 2023. PMID: 37898124 Free article.
A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body.
Sun S, Ma S, Cai Y, Wang S, Ren J, Yang Y, Ping J, Wang X, Zhang Y, Yan H, Li W, Esteban CR, Yu Y, Liu F, Izpisua Belmonte JC, Zhang W, Qu J, Liu GH. Sun S, et al. Among authors: izpisua belmonte jc. Innovation (Camb). 2023 Jan 5;4(1):100380. doi: 10.1016/j.xinn.2023.100380. eCollection 2023 Jan 30. Innovation (Camb). 2023. PMID: 36747595 Free PMC article.
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging.
Zhang H, Li J, Yu Y, Ren J, Liu Q, Bao Z, Sun S, Liu X, Ma S, Liu Z, Yan K, Wu Z, Fan Y, Sun X, Zhang Y, Ji Q, Cheng F, Wei PH, Ma X, Zhang S, Xie Z, Niu Y, Wang YJ, Han JJ, Jiang T, Zhao G, Ji W, Izpisua Belmonte JC, Wang S, Qu J, Zhang W, Liu GH. Zhang H, et al. Among authors: izpisua belmonte jc. Cell Rep. 2023 Jun 27;42(6):112593. doi: 10.1016/j.celrep.2023.112593. Epub 2023 May 31. Cell Rep. 2023. PMID: 37261950 Free article.
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging.
Zhang H, Li J, Yu Y, Ren J, Liu Q, Bao Z, Sun S, Liu X, Ma S, Liu Z, Yan K, Wu Z, Fan Y, Sun X, Zhang Y, Ji Q, Cheng F, Wei PH, Ma X, Zhang S, Xie Z, Niu Y, Wang YJ, Han JJ, Jiang T, Zhao G, Ji W, Izpisua Belmonte JC, Wang S, Qu J, Zhang W, Liu GH. Zhang H, et al. Among authors: izpisua belmonte jc. Cell Rep. 2023 Nov 28;42(11):113396. doi: 10.1016/j.celrep.2023.113396. Epub 2023 Oct 31. Cell Rep. 2023. PMID: 37910499 Free article. No abstract available.
Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland.
Wang Q, Wang X, Liu B, Ma S, Zhang F, Sun S, Jing Y, Fan Y, Ding Y, Xiong M, Li J, Zhai Q, Zheng Y, Liu C, Xu G, Yang J, Wang S, Ye J, Izpisua Belmonte JC, Qu J, Liu GH, Zhang W. Wang Q, et al. Among authors: izpisua belmonte jc. Nat Aging. 2024 Mar;4(3):396-413. doi: 10.1038/s43587-024-00588-1. Epub 2024 Mar 19. Nat Aging. 2024. PMID: 38503993
Metformin decelerates aging clock in male monkeys.
Yang Y, Lu X, Liu N, Ma S, Zhang H, Zhang Z, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Rodriguez Esteban C, Song M, Wang S, Zhao G, Li W, Izpisua Belmonte JC, Qu J, Zhang W, Liu GH. Yang Y, et al. Among authors: izpisua belmonte jc. Cell. 2024 Oct 31;187(22):6358-6378.e29. doi: 10.1016/j.cell.2024.08.021. Epub 2024 Sep 12. Cell. 2024. PMID: 39270656
Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging.
Ma S, Ji Z, Zhang B, Geng L, Cai Y, Nie C, Li J, Zuo Y, Sun Y, Xu G, Liu B, Ai J, Liu F, Zhao L, Zhang J, Zhang H, Sun S, Huang H, Zhang Y, Ye Y, Fan Y, Zheng F, Hu J, Zhang B, Li J, Feng X, Zhang F, Zhuang Y, Li T, Yu Y, Bao Z, Pan S, Rodriguez Esteban C, Liu Z, Deng H, Wen F, Song M, Wang S, Zhu G, Yang J, Jiang T, Song W, Izpisua Belmonte JC, Qu J, Zhang W, Gu Y, Liu GH. Ma S, et al. Among authors: izpisua belmonte jc. Cell. 2024 Nov 27;187(24):7025-7044.e34. doi: 10.1016/j.cell.2024.10.019. Epub 2024 Nov 4. Cell. 2024. PMID: 39500323
Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo.
Liu M, Zhang C, Gong X, Zhang T, Lian MM, Chew EGY, Cardilla A, Suzuki K, Wang H, Yuan Y, Li Y, Naik MY, Wang Y, Zhou B, Soon WZ, Aizawa E, Li P, Low JH, Tandiono M, Montagud E, Moya-Rull D, Rodriguez Esteban C, Luque Y, Fang M, Khor CC, Montserrat N, Campistol JM, Izpisua Belmonte JC, Foo JN, Xia Y. Liu M, et al. Among authors: izpisua belmonte jc. Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8. doi: 10.1016/j.stem.2023.12.003. Cell Stem Cell. 2024. PMID: 38181751 Free article.
437 results