Kang SC - Search Results

1

Differential cell cycle checkpoint evasion by PTEN germline mutations associated with dichotomous phenotypes of cancer versus autism spectrum disorder.

Hitomi M, Venegas J, Kang SC, Eng C. Hitomi M, et al. Among authors: kang sc. Oncogene. 2023 Dec;42(50):3698-3707. doi: 10.1038/s41388-023-02867-4. Epub 2023 Nov 1. Oncogene. 2023. PMID: 37907589

2

Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation.

Kang SC, Jaini R, Hitomi M, Lee H, Sarn N, Thacker S, Eng C. Kang SC, et al. Mol Autism. 2020 Jun 1;11(1):43. doi: 10.1186/s13229-020-00337-2. Mol Autism. 2020. PMID: 32487265 Free PMC article.

3

Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids.

Kang SC, Sarn NB, Venegas J, Tan Z, Hitomi M, Eng C. Kang SC, et al. Mol Psychiatry. 2024 Jun;29(6):1767-1781. doi: 10.1038/s41380-023-02325-3. Epub 2023 Nov 29. Mol Psychiatry. 2024. PMID: 38030818

4

Aggregation of prion protein with insertion mutations is proportional to the number of inserts.

Yu S, Yin S, Li C, Wong P, Chang B, Xiao F, Kang SC, Yan H, Xiao G, Tien P, Sy MS. Yu S, et al. Among authors: kang sc. Biochem J. 2007 Apr 15;403(2):343-51. doi: 10.1042/BJ20061592. Biochem J. 2007. PMID: 17187581 Free PMC article.

5

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans.

Yin S, Pham N, Yu S, Li C, Wong P, Chang B, Kang SC, Biasini E, Tien P, Harris DA, Sy MS. Yin S, et al. Among authors: kang sc. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7546-51. doi: 10.1073/pnas.0610827104. Epub 2007 Apr 24. Proc Natl Acad Sci U S A. 2007. PMID: 17456603 Free PMC article.

6

Normal cellular prion protein with a methionine at position 129 has a more exposed helix 1 and is more prone to aggregate.

Pham N, Yin S, Yu S, Wong P, Kang SC, Li C, Sy MS. Pham N, et al. Among authors: kang sc. Biochem Biophys Res Commun. 2008 Apr 18;368(4):875-81. doi: 10.1016/j.bbrc.2008.01.172. Epub 2008 Feb 12. Biochem Biophys Res Commun. 2008. PMID: 18275852

7

Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.

Yu S, Yin S, Pham N, Wong P, Kang SC, Petersen RB, Li C, Sy MS. Yu S, et al. Among authors: kang sc. FEBS J. 2008 Nov;275(22):5564-75. doi: 10.1111/j.1742-4658.2008.06680.x. FEBS J. 2008. PMID: 18959744 Free PMC article.

8

Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack.

Yin S, Yu S, Li C, Wong P, Chang B, Xiao F, Kang SC, Yan H, Xiao G, Grassi J, Tien P, Sy MS. Yin S, et al. Among authors: kang sc. J Biol Chem. 2006 Apr 21;281(16):10698-705. doi: 10.1074/jbc.M511819200. Epub 2006 Feb 14. J Biol Chem. 2006. PMID: 16478730 Free article.

9

Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X).

Li C, Wong P, Pan T, Xiao F, Yin S, Chang B, Kang SC, Ironside J, Sy MS. Li C, et al. Among authors: kang sc. Biochem J. 2007 Sep 1;406(2):333-41. doi: 10.1042/BJ20061857. Biochem J. 2007. PMID: 17497959 Free PMC article.

10

Guanidine hydrochloride extraction and detection of prion proteins in mouse and hamster prion diseases by ELISA.

Kang SC, Li R, Wang C, Pan T, Liu T, Rubenstein R, Barnard G, Wong BS, Sy MS. Kang SC, et al. J Pathol. 2003 Apr;199(4):534-41. doi: 10.1002/path.1294. J Pathol. 2003. PMID: 12635145

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