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The SGLT2 inhibitor dapagliflozin improves kidney function in glycogen storage disease XI.
Trepiccione F, Iervolino A, D'Acierno M, Siccardi S, Costanzo V, Sardella D, De La Motte LR, D'Apolito L, Miele A, Perna AF, Capolongo G, Zacchia M, Frische S, Nielsen R, Staiano L, Sambri I, De Cegli R, Unwin R, Eladari D, Capasso G. Trepiccione F, et al. Among authors: costanzo v. Sci Transl Med. 2023 Nov;15(720):eabn4214. doi: 10.1126/scitranslmed.abn4214. Epub 2023 Nov 1. Sci Transl Med. 2023. PMID: 37910600
Dapagliflozin Prevents Kidney Glycogen Accumulation and Improves Renal Proximal Tubule Cell Functions in a Mouse Model of Glycogen Storage Disease Type 1b.
D'Acierno M, Resaz R, Iervolino A, Nielsen R, Sardella D, Siccardi S, Costanzo V, D'Apolito L, Suzumoto Y, Segalerba D, Astigiano S, Perna AF, Capasso G, Eva A, Trepiccione F. D'Acierno M, et al. Among authors: costanzo v. J Am Soc Nephrol. 2022 Oct;33(10):1864-1875. doi: 10.1681/ASN.2021070935. Epub 2022 Jul 12. J Am Soc Nephrol. 2022. PMID: 35820785 Free PMC article.
The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo.
Engbjerg JS, Costanzo V, Sardella D, Bordoni L, Jakobsen S, D'Apolito L, Frøkiær J, Trepiccione F, Capasso G, Frische S. Engbjerg JS, et al. Among authors: costanzo v. Mol Imaging. 2022 Mar 22;2022:7908357. doi: 10.1155/2022/7908357. eCollection 2022. Mol Imaging. 2022. PMID: 35418808 Free PMC article.
Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation.
Prosperi F, Suzumoto Y, Marzuillo P, Costanzo V, Jelen S, Iervolino A, Guarino S, La Manna A, Miraglia Del Giudice E, Perna AF, Zacchia M, Cordat E, Capasso G, Trepiccione F. Prosperi F, et al. Among authors: costanzo v. Sci Rep. 2020 Oct 2;10(1):16383. doi: 10.1038/s41598-020-73089-x. Sci Rep. 2020. PMID: 33009446 Free PMC article.
Dysregulation of Principal Cell miRNAs Facilitates Epigenetic Regulation of AQP2 and Results in Nephrogenic Diabetes Insipidus.
Petrillo F, Iervolino A, Angrisano T, Jelen S, Costanzo V, D'Acierno M, Cheng L, Wu Q, Guerriero I, Mazzarella MC, De Falco A, D'Angelo F, Ceccarelli M, Caraglia M, Capasso G, Fenton RA, Trepiccione F. Petrillo F, et al. Among authors: costanzo v. J Am Soc Nephrol. 2021 Jun 1;32(6):1339-1354. doi: 10.1681/ASN.2020010031. Epub 2021 Mar 16. J Am Soc Nephrol. 2021. PMID: 33727367 Free PMC article.
Early-onset cancers: Biological bases and clinical implications.
Mauri G, Patelli G, Sartore-Bianchi A, Abrignani S, Bodega B, Marsoni S, Costanzo V, Bachi A, Siena S, Bardelli A. Mauri G, et al. Among authors: costanzo v. Cell Rep Med. 2024 Sep 17;5(9):101737. doi: 10.1016/j.xcrm.2024.101737. Epub 2024 Sep 10. Cell Rep Med. 2024. PMID: 39260369 Free PMC article. Review.
A high-throughput screening identifies MCM chromatin loading inhibitors targeting cells with increased replication origins.
Falbo L, Técher H, Sannino V, Robusto M, Fagà G, Pezzimenti F, Romeo F, Colombo LG, Vultaggio S, Fancelli D, Monzani S, Cecatiello V, Pasqualato S, Varasi M, Mercurio C, Costanzo V. Falbo L, et al. Among authors: costanzo v. iScience. 2024 Jul 22;27(8):110567. doi: 10.1016/j.isci.2024.110567. eCollection 2024 Aug 16. iScience. 2024. PMID: 39184446 Free PMC article.
RAD51 protects abasic sites to prevent replication fork breakage.
Hanthi YW, Ramirez-Otero MA, Appleby R, De Antoni A, Joudeh L, Sannino V, Waked S, Ardizzoia A, Barra V, Fachinetti D, Pellegrini L, Costanzo V. Hanthi YW, et al. Among authors: costanzo v. Mol Cell. 2024 Aug 22;84(16):3026-3043.e11. doi: 10.1016/j.molcel.2024.07.004. Mol Cell. 2024. PMID: 39178838 Free article.
147 results