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Prognostic and predictive value of human equilibrative nucleoside transporter 1 (hENT1) in extrahepatic cholangiocarcinoma: a translational study.
Boyd LNC, Nooijen LE, Ali M, Puik JR, Moustaquim J, Fraga Rodrigues SM, Broos R, Belkouz A, Meijer LL, Le Large TYS, Erdmann JI, Hooijer GKJ, Heger M, Van Laarhoven HWM, Roos E, Kazemier G, Giovannetti E, Verheij J, Klümpen HJ. Boyd LNC, et al. Among authors: klumpen hj. Front Pharmacol. 2023 Oct 18;14:1274692. doi: 10.3389/fphar.2023.1274692. eCollection 2023. Front Pharmacol. 2023. PMID: 37920204 Free PMC article.
Phase II Study of BEZ235 versus Everolimus in Patients with Mammalian Target of Rapamycin Inhibitor-Naïve Advanced Pancreatic Neuroendocrine Tumors.
Salazar R, Garcia-Carbonero R, Libutti SK, Hendifar AE, Custodio A, Guimbaud R, Lombard-Bohas C, Ricci S, Klümpen HJ, Capdevila J, Reed N, Walenkamp A, Grande E, Safina S, Meyer T, Kong O, Salomon H, Tavorath R, Yao JC. Salazar R, et al. Among authors: klumpen hj. Oncologist. 2018 Jul;23(7):766-e90. doi: 10.1634/theoncologist.2017-0144. Epub 2017 Dec 14. Oncologist. 2018. PMID: 29242283 Free PMC article. Clinical Trial.
Trends in incidence, diagnosis, treatment and survival of hepatocellular carcinoma in a low-incidence country: Data from the Netherlands in the period 2009-2016.
Reinders MTM, van Meer S, Burgmans MC, de Jong KP, Klümpen HJ, de Man RA, Ramsoekh DS, Sprengers D, Tjwa ETTL, de Vos-Geelen J, van Erpecum KJ, van der Geest LGM; Dutch Hepatocellular & Cholangiocarcinoma Group (DHCG). Reinders MTM, et al. Among authors: klumpen hj. Eur J Cancer. 2020 Sep;137:214-223. doi: 10.1016/j.ejca.2020.07.008. Epub 2020 Aug 13. Eur J Cancer. 2020. PMID: 32799035
Short-term fasting alters cytochrome P450-mediated drug metabolism in humans.
Lammers LA, Achterbergh R, de Vries EM, van Nierop FS, Klümpen HJ, Soeters MR, Boelen A, Romijn JA, Mathôt RA. Lammers LA, et al. Among authors: klumpen hj. Drug Metab Dispos. 2015 Jun;43(6):819-28. doi: 10.1124/dmd.114.062299. Epub 2015 Mar 20. Drug Metab Dispos. 2015. PMID: 25795462 Clinical Trial.
Alternating Treatment With Pazopanib and Everolimus vs Continuous Pazopanib to Delay Disease Progression in Patients With Metastatic Clear Cell Renal Cell Cancer: The ROPETAR Randomized Clinical Trial.
Cirkel GA, Hamberg P, Sleijfer S, Loosveld OJL, Dercksen MW, Los M, Polee MB, van den Berkmortel F, Aarts MJ, Beerepoot LV, Groenewegen G, Lolkema MP, Tascilar M, Portielje JEA, Peters FPJ, Klümpen HJ, van der Noort V, Haanen JBAG, Voest EE; Dutch WIN-O Consortium. Cirkel GA, et al. Among authors: klumpen hj. JAMA Oncol. 2017 Apr 1;3(4):501-508. doi: 10.1001/jamaoncol.2016.5202. JAMA Oncol. 2017. PMID: 27918762 Clinical Trial.
Inhibitors of mTOR.
Klümpen HJ, Beijnen JH, Gurney H, Schellens JH. Klümpen HJ, et al. Oncologist. 2010;15(12):1262-9. doi: 10.1634/theoncologist.2010-0196. Epub 2010 Dec 8. Oncologist. 2010. PMID: 21147869 Free PMC article. Review.
Dose calculation of anticancer drugs.
Gao B, Klumpen HJ, Gurney H. Gao B, et al. Among authors: klumpen hj. Expert Opin Drug Metab Toxicol. 2008 Oct;4(10):1307-19. doi: 10.1517/17425255.4.10.1307. Expert Opin Drug Metab Toxicol. 2008. PMID: 18798700 Review.
Efficacy and safety of cabozantinib for patients with advanced hepatocellular carcinoma based on albumin-bilirubin grade.
Kelley RK, Miksad R, Cicin I, Chen Y, Klümpen HJ, Kim S, Lin ZZ, Youkstetter J, Hazra S, Sen S, Cheng AL, El-Khoueiry AB, Meyer T, Abou-Alfa GK. Kelley RK, et al. Among authors: klumpen hj. Br J Cancer. 2022 Mar;126(4):569-575. doi: 10.1038/s41416-021-01532-5. Epub 2021 Oct 7. Br J Cancer. 2022. PMID: 34621044 Free PMC article. Clinical Trial.
151 results