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Page 1
Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.
Moura PL, Mortera-Blanco T, Hofman IJ, Todisco G, Kretzschmar WW, Björklund AC, Creignou M, Hagemann-Jensen M, Ziegenhain C, Cabrerizo Granados D, Barbosa I, Walldin G, Jansson M, Ashley N, Mead AJ, Lundin V, Dimitriou M, Yoshizato T, Woll PS, Ogawa S, Sandberg R, Jacobsen SEW, Hellström-Lindberg E. Moura PL, et al. Among authors: hofman ij. Cancer Res. 2024 Jan 16;84(2):211-225. doi: 10.1158/0008-5472.CAN-23-3038. Cancer Res. 2024. PMID: 37921711 Free PMC article.
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.
Todisco G, Creignou M, Bernard E, Björklund AC, Moura PL, Tesi B, Mortera-Blanco T, Sander B, Jansson M, Walldin G, Barbosa I, Reinsbach SE, Hofman IJ, Nilsson C, Yoshizato T, Dimitriou M, Chang D, Olafsdottir S, Venckute Larsson S, Tobiasson M, Malcovati L, Woll P, Jacobsen SEW, Papaemmanuil E, Hellström-Lindberg E. Todisco G, et al. Among authors: hofman ij. Clin Cancer Res. 2023 Oct 13;29(20):4256-4267. doi: 10.1158/1078-0432.CCR-23-0538. Clin Cancer Res. 2023. PMID: 37498312 Free PMC article.
The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS.
Hofman IJF, Mortera-Blanco T, Moura PL, Vestlund J, Larsson SV, Elvarsdottir EM, Walldin G, Tobiasson M, Sander B, Dimitriou M, Jacobsen SW, Woll PS, Jädersten M, Hellström-Lindberg E. Hofman IJF, et al. Blood Adv. 2022 Aug 23;6(16):4705-4709. doi: 10.1182/bloodadvances.2022007858. Blood Adv. 2022. PMID: 35728121 Free PMC article. No abstract available.
How Ribosomes Translate Cancer.
Sulima SO, Hofman IJF, De Keersmaecker K, Dinman JD. Sulima SO, et al. Among authors: hofman ijf. Cancer Discov. 2017 Oct;7(10):1069-1087. doi: 10.1158/2159-8290.CD-17-0550. Epub 2017 Sep 18. Cancer Discov. 2017. PMID: 28923911 Free PMC article. Review.
Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma.
Hofman IJF, Patchett S, van Duin M, Geerdens E, Verbeeck J, Michaux L, Delforge M, Sonneveld P, Johnson AW, De Keersmaecker K. Hofman IJF, et al. Haematologica. 2017 Aug;102(8):e317-e320. doi: 10.3324/haematol.2016.162198. Epub 2017 Apr 20. Haematologica. 2017. PMID: 28428269 Free PMC article. No abstract available.
RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response.
Hofman IJF, van Duin M, De Bruyne E, Fancello L, Mulligan G, Geerdens E, Garelli E, Mancini C, Lemmens H, Delforge M, Vandenberghe P, Wlodarska I, Aspesi A, Michaux L, Vanderkerken K, Sonneveld P, De Keersmaecker K. Hofman IJF, et al. Leukemia. 2017 Aug;31(8):1706-1714. doi: 10.1038/leu.2016.370. Epub 2016 Dec 2. Leukemia. 2017. PMID: 27909306 Free PMC article.