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MDA-9/Syntenin in the tumor and microenvironment defines prostate cancer bone metastasis.
Maji S, Pradhan AK, Kumar A, Bhoopathi P, Mannangatti P, Guo C, Windle JJ, Subler MA, Wang XY, Semmes OJ, Nyalwidhe JO, Mukhopadhyay N, Paul AK, Hatfield B, Levit MM, Madan E, Sarkar D, Emdad L, Cohen DJ, Gogna R, Cavenee WK, Das SK, Fisher PB. Maji S, et al. Among authors: mannangatti p. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2307094120. doi: 10.1073/pnas.2307094120. Epub 2023 Nov 3. Proc Natl Acad Sci U S A. 2023. PMID: 37922327 Free PMC article.
Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis.
Pradhan AK, Modi J, Maji S, Kumar A, Bhoopathi P, Mannangatti P, Guo C, Afosah DK, Mochel MC, Mukhopadhyay ND, Kirkwood JM, Wang XY, Desai UR, Sarkar D, Emdad L, Das SK, Fisher PB. Pradhan AK, et al. Among authors: mannangatti p. Mol Cancer Ther. 2023 Oct 2;22(10):1115-1127. doi: 10.1158/1535-7163.MCT-22-0653. Mol Cancer Ther. 2023. PMID: 37721536
Cytoplasmic-delivery of polyinosine-polycytidylic acid inhibits pancreatic cancer progression increasing survival by activating Stat1-CCL2-mediated immunity.
Bhoopathi P, Kumar A, Pradhan AK, Maji S, Mannangatti P, Windle JJ, Subler MA, Zhang D, Vudatha V, Trevino JG, Madan E, Atfi A, Sarkar D, Gogna R, Das SK, Emdad L, Fisher PB. Bhoopathi P, et al. Among authors: mannangatti p. J Immunother Cancer. 2023 Nov;11(11):e007624. doi: 10.1136/jitc-2023-007624. J Immunother Cancer. 2023. PMID: 37935566 Free PMC article.
Noninvasive therapy of brain cancer using a unique systemic delivery methodology with a cancer terminator virus.
Bhoopathi P, Mannangatti P, Pradhan AK, Kumar A, Maji S, Lang FF, Klibanov AL, Madan E, Cavenee WK, Keoprasert T, Sun D, Bjerkvig R, Thorsen F, Gogna R, Das SK, Emdad L, Fisher PB. Bhoopathi P, et al. Among authors: mannangatti p. J Cell Physiol. 2024 Aug;239(8):e31302. doi: 10.1002/jcp.31302. Epub 2024 May 22. J Cell Physiol. 2024. PMID: 38775127
Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells.
Madan E, Palma AM, Vudatha V, Kumar A, Bhoopathi P, Wilhelm J, Bernas T, Martin PC, Bilolikar G, Gogna A, Peixoto ML, Dreier I, Araujo TF, Garre E, Gustafsson A, Dorayappan KDP, Mamidi N, Sun Z, Yekelchyk M, Accardi D, Olsen AL, Lin L, Titelman AA, Bianchi M, Jessmon P, Farid EA, Pradhan AK, Neufeld L, Yeini E, Maji S, Pelham CJ, Kim H, Oh D, Rolfsnes HO, Marques RC, Lu A, Nagane M, Chaudhary S, Gupta K, Gogna KC, Bigio A, Bhoopathi K, Mannangatti P, Achary KG, Akhtar J, Belião S, Das S, Correia I, da Silva CL, Fialho AM, Poellmann MJ, Javius-Jones K, Hawkridge AM, Pal S, Shree KS, Rakha EA, Khurana S, Xiao G, Zhang D, Rijal A, Lyons C, Grossman SR, Turner DP, Pillappa R, Prakash K, Gupta G, Robinson GLWG, Koblinski J, Wang H, Singh G, Singh S, Rayamajhi S, Bacolod MD, Richards H, Sayeed S, Klein KP, Chelmow D, Satchi-Fainaro R, Selvendiran K, Connolly D, Thorsen FA, Bjerkvig R, Nephew KP, Idowu MO, Kühnel MP, Moskaluk C, Hong S, Redmond WL, Landberg G, Lopez-Beltran A, Poklepovic AS, Sanyal A, Fisher PB, Church GM, Menon U, Drapkin R, Godwin AK, Luo Y, Ackermann M, Tzankov A, Mertz KD, Jonigk D, Tsung A, Sidransky D, Trevino J, Saavedra AP, Winn R, Won KJ, Moreno E, Gogna … See abstract for full author list ➔ Madan E, et al. Among authors: mannangatti p. Nat Biotechnol. 2024 Dec 9. doi: 10.1038/s41587-024-02453-3. Online ahead of print. Nat Biotechnol. 2024. PMID: 39653752
Conversion of a Non-Cancer-Selective Promoter into a Cancer-Selective Promoter.
Bhoopathi P, Pradhan AK, Kumar A, Maji S, Mannangatti P, Deng X, Bandyopadhyay D, Sarkar D, Wang XY, Landry JW, Das SK, Emdad L, Fisher PB. Bhoopathi P, et al. Among authors: mannangatti p. Cancers (Basel). 2022 Mar 15;14(6):1497. doi: 10.3390/cancers14061497. Cancers (Basel). 2022. PMID: 35326649 Free PMC article.
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